Linked Life Data

18161576

Source:http://linkedlifedata.com/resource/pubmed/id/18161576

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2007-12-28
pubmed:abstractText
The present study investigates renal inner medullary collecting duct (mIMCD3) cells and human embryonic kidney cells (HEK293) for evaluation of cytotoxicity of nephrotoxic compounds. The 24 h LC(50) values for cisplatin, paraquat and ibuprofen in mIMCD3 cells were 135, 155 and 3600 microM, respectively. The 24 h LC(50) values for paraquat and ibuprofen in HEK293 cells were 180 and 1000 microM, respectively. Effects of hyperosmolality on cytotoxicity of paraquat were additive in mIMCD3 cells. These data demonstrate that renal hyperosmolality has an additive effect on cytoxicity of paraquat.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0360-1234
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
71-4
pubmed:dateRevised
2009-7-21
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Determination of cytotoxicity of nephrotoxins on murine and human kidney cell lines.
pubmed:affiliation
Department of Entomology and Cancer Research Center, University of California-Davis, CA, USA. eunkee.park@ddb.nsw.gov.au
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural