Linked Life Data

18077774

Source:http://linkedlifedata.com/resource/pubmed/id/18077774

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2007-12-13
pubmed:abstractText
Investigations of the role cytokines play in preterm birth are complicated by a number of methodologic issues that arise as to the most feasible and efficient methods to measure cytokines. The purpose of this article is to review methodologic issues surrounding the measurement of vaginal and cervical cytokines, specifically IL-1beta, IL-6, and TNF-alpha, in pregnant women experiencing preterm labor. Specifically, two quantification methods, weight and protein assay, and cytokine specimens from two different sites, vaginal and cervical, were compared. There were no significant correlations between cytokine levels using the protein versus weight quantification method. The weight method had more negative values and thus the protein quantification method was more accurate. There were high correlations between cervical and vaginal IL-1beta levels and IL-6 levels, but cervical and vaginal TNF-alpha levels were not correlated.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1099-8004
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
215-22
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Cervical and vaginal cytokine determinations in pregnant women: methodologic issues.
pubmed:affiliation
New York University, New York, NY 10010, USA. Susan.gennaro@nyu.edu
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural