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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2008-5-15
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pubmed:abstractText |
Oxidative damage promotes atherosclerosis. Manganese superoxide dismutase (MnSOD) is an antioxidant enzyme localized in mitochondria. We investigated the associations of the MnSOD polymorphism (valine-to-alanine in the mitochondrial-targeting domain) with its activity in leukocytes, with macrophage apoptosis by oxidized low-density lipoprotein (oxLDL), and with coronary artery disease (CAD).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1522-9645
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pubmed:author |
pubmed-author:AizawaTadanoriT,
pubmed-author:AyabeSeijiS,
pubmed-author:FujimotoHajimeH,
pubmed-author:HashimotoHidekiH,
pubmed-author:ImaiYasushiY,
pubmed-author:KobayashiHisaeH,
pubmed-author:NagaiRyozoR,
pubmed-author:OgasawaraKenK,
pubmed-author:OhnoMinoruM,
pubmed-author:TaguchiJun-IchiJ,
pubmed-author:YamakadoMinoruM
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pubmed:issnType |
Electronic
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1267-74
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pubmed:meshHeading |
pubmed-meshheading:17967822-Adult,
pubmed-meshheading:17967822-Aged,
pubmed-meshheading:17967822-Aged, 80 and over,
pubmed-meshheading:17967822-Apoptosis,
pubmed-meshheading:17967822-Coronary Artery Disease,
pubmed-meshheading:17967822-Female,
pubmed-meshheading:17967822-Humans,
pubmed-meshheading:17967822-Leukocytes,
pubmed-meshheading:17967822-Lipoproteins, LDL,
pubmed-meshheading:17967822-Macrophages,
pubmed-meshheading:17967822-Male,
pubmed-meshheading:17967822-Middle Aged,
pubmed-meshheading:17967822-Myocardial Infarction,
pubmed-meshheading:17967822-Polymorphism, Genetic,
pubmed-meshheading:17967822-Superoxide Dismutase
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pubmed:year |
2008
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pubmed:articleTitle |
Manganese superoxide dismutase polymorphism affects the oxidized low-density lipoprotein-induced apoptosis of macrophages and coronary artery disease.
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pubmed:affiliation |
Department of Cardiovascular Medicine, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
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pubmed:publicationType |
Journal Article
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