17962626

Source:http://linkedlifedata.com/resource/pubmed/id/17962626

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0003009, umls-concept:C0011155, umls-concept:C0014257, umls-concept:C0020564, umls-concept:C0021760, umls-concept:C0205263, umls-concept:C0277785
pubmed:issue	12
pubmed:dateCreated	2007-11-21
pubmed:abstractText	The goal of this study was to test the hypothesis that IL-6 mediates the increases in superoxide, vascular hypertrophy, and endothelial dysfunction in response to angiotensin II (Ang II).
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/HL-38901, http://linkedlifedata.com/resource/pubmed/grant/HL-62984, http://linkedlifedata.com/resource/pubmed/grant/NS-24621
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9505803
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Acetylcholine, http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II, http://linkedlifedata.com/resource/pubmed/chemical/Cybb protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6, http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins, http://linkedlifedata.com/resource/pubmed/chemical/NADPH Oxidase, http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type II, http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type III, http://linkedlifedata.com/resource/pubmed/chemical/Nos3 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Superoxides, http://linkedlifedata.com/resource/pubmed/chemical/Vasodilator Agents
pubmed:status	MEDLINE
pubmed:month	Dec
pubmed:issn	1524-4636
pubmed:author	pubmed-author:DidionSean PSP, pubmed-author:FaraciFrank MFM, pubmed-author:JohnsonAndrew WAW, pubmed-author:KinzenbawDale ADA, pubmed-author:SchraderLaura ILI
pubmed:issnType	Electronic
pubmed:volume	27
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	2576-81
pubmed:dateRevised	2009-11-19
pubmed:meshHeading	pubmed-meshheading:17962626-Acetylcholine, pubmed-meshheading:17962626-Angiotensin II, pubmed-meshheading:17962626-Animals, pubmed-meshheading:17962626-Blood Pressure, pubmed-meshheading:17962626-Carotid Arteries, pubmed-meshheading:17962626-Dose-Response Relationship, Drug, pubmed-meshheading:17962626-Endothelium, Vascular, pubmed-meshheading:17962626-Hypertrophy, pubmed-meshheading:17962626-Interleukin-6, pubmed-meshheading:17962626-Male, pubmed-meshheading:17962626-Membrane Glycoproteins, pubmed-meshheading:17962626-Mice, pubmed-meshheading:17962626-Mice, Inbred C57BL, pubmed-meshheading:17962626-Mice, Knockout, pubmed-meshheading:17962626-NADPH Oxidase, pubmed-meshheading:17962626-Nitric Oxide Synthase Type II, pubmed-meshheading:17962626-Nitric Oxide Synthase Type III, pubmed-meshheading:17962626-Oxidative Stress, pubmed-meshheading:17962626-RNA, Messenger, pubmed-meshheading:17962626-Superoxides, pubmed-meshheading:17962626-Time Factors, pubmed-meshheading:17962626-Vasodilation, pubmed-meshheading:17962626-Vasodilator Agents
pubmed:year	2007
pubmed:articleTitle	IL-6 deficiency protects against angiotensin II induced endothelial dysfunction and hypertrophy.
pubmed:affiliation	Department of Internal Medicine, Division of Cardiovascular Medicine, 340-G Eckstein Medical Research Building, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural