|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2007-11-9
|
|
pubmed:abstractText |
Dihydropyrimidine dehydrogenase (DPD) is a rate-limiting enzyme for the degradation of 5-fluorouracil. The effect of long-term treatment with oral fluoropyrimidines on DPD activity has not been investigated. This study was conducted to examine changes in DPD activity in peripheral mononuclear cells (PMNC) during long-term treatment with oral uracil and tegafur (UFT) for colorectal cancer.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1421-9794
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
(c) 2007 S. Karger AG, Basel.
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
53
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
442-5
|
|
pubmed:dateRevised |
2009-11-11
|
|
pubmed:meshHeading |
pubmed-meshheading:17952005-Administration, Oral,
pubmed-meshheading:17952005-Adult,
pubmed-meshheading:17952005-Aged,
pubmed-meshheading:17952005-Aged, 80 and over,
pubmed-meshheading:17952005-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:17952005-Chemotherapy, Adjuvant,
pubmed-meshheading:17952005-Colorectal Neoplasms,
pubmed-meshheading:17952005-Dihydrouracil Dehydrogenase (NADP),
pubmed-meshheading:17952005-Female,
pubmed-meshheading:17952005-Humans,
pubmed-meshheading:17952005-Male,
pubmed-meshheading:17952005-Middle Aged,
pubmed-meshheading:17952005-Prospective Studies,
pubmed-meshheading:17952005-Tegafur,
pubmed-meshheading:17952005-Time Factors,
pubmed-meshheading:17952005-Uracil
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Dihydropyrimidine dehydrogenase activity during long-term adjuvant treatment with oral uracil and tegafur for colorectal cancer.
|
|
pubmed:affiliation |
Department of Surgery, Tokai University School of Medicine, Isehara, Japan. sadahiro@is.icc.u-tokai.ac.jp
|
|
pubmed:publicationType |
Journal Article
|
