17854487

Source:http://linkedlifedata.com/resource/pubmed/id/17854487

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0003364, umls-concept:C0005823, umls-concept:C0013216, umls-concept:C0017337, umls-concept:C0020538, umls-concept:C1412231, umls-concept:C1704675
pubmed:dateCreated	2007-11-8
pubmed:abstractText	As part of the NHLBI Family Blood Pressure Program, the Genetic Epidemiology Network of Arteriopathy (GENOA) recruited 575 sibships (n = 1583 individuals) from Rochester, MN who had at least two hypertensive siblings diagnosed before age 60. Linkage analysis identified a region on chromosome 2 that was investigated using 70 single nucleotide polymorphisms (SNPs) typed in 7 positional candidate genes, including adducin 2 (ADD2).
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/HL54457, http://linkedlifedata.com/resource/pubmed/grant/HL68737
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/100968552
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/ADD2 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Antihypertensive Agents, http://linkedlifedata.com/resource/pubmed/chemical/Cytoskeletal Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Genetic Markers
pubmed:status	MEDLINE
pubmed:issn	1471-2350
pubmed:author	pubmed-author:BarkleyRuth AnnRA, pubmed-author:BoerwinkleEricE, pubmed-author:HamonSara CSC, pubmed-author:KardiaSharon L RSL, pubmed-author:SunYan VYV, pubmed-author:TurnerStephen TST
pubmed:issnType	Electronic
pubmed:volume	8
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	61
pubmed:dateRevised	2010-9-15
pubmed:meshHeading	pubmed-meshheading:17854487-Analysis of Variance, pubmed-meshheading:17854487-Antihypertensive Agents, pubmed-meshheading:17854487-Blood Pressure, pubmed-meshheading:17854487-Cytoskeletal Proteins, pubmed-meshheading:17854487-Genetic Markers, pubmed-meshheading:17854487-Genetic Variation, pubmed-meshheading:17854487-Genotype, pubmed-meshheading:17854487-Humans, pubmed-meshheading:17854487-Hypertension, pubmed-meshheading:17854487-Linkage Disequilibrium, pubmed-meshheading:17854487-Middle Aged, pubmed-meshheading:17854487-Models, Genetic, pubmed-meshheading:17854487-Polymorphism, Single Nucleotide, pubmed-meshheading:17854487-Predictive Value of Tests, pubmed-meshheading:17854487-Regression Analysis
pubmed:year	2007
pubmed:articleTitle	Interactions between the adducin 2 gene and antihypertensive drug therapies in determining blood pressure in people with hypertension.
pubmed:affiliation	Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA. skardia@umich.edu
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't

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