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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1992-3-10
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pubmed:abstractText |
Hepatitis B serology was performed on 270 family members of 78 hepatitis B carriers and hepatitis B e antigen status determined in those found to be HBsAg positive. The mean age of index patients was 38 years (range 3-74) and that of family members was 28 years (range 1-71). 67 family members (25%) were HBsAg positive. The proportions of family members positive for HBsAg and those negative for HBsAg but positive for anti-HBs and/or anti-HBc were 25% and 20% for children, 10% and 68% for spouses, 36% and 26% for siblings and 29% and 55% for parents. For children of index parents the proportions positive for HBsAg and those negative for HBsAg but positive for anti-HBs and/or anti-HBc were similar whether the index patient was the mother (24% and 24%) or the father (26% and 18%). Our results suggest that horizontal transmission is a significant mode of spread of hepatitis B within the family in Singapore.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0035-9203
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
85
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
656-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1781002-Adolescent,
pubmed-meshheading:1781002-Adult,
pubmed-meshheading:1781002-Aged,
pubmed-meshheading:1781002-Carrier State,
pubmed-meshheading:1781002-Child,
pubmed-meshheading:1781002-Child, Preschool,
pubmed-meshheading:1781002-Family,
pubmed-meshheading:1781002-Female,
pubmed-meshheading:1781002-Hepatitis B,
pubmed-meshheading:1781002-Hepatitis B Surface Antigens,
pubmed-meshheading:1781002-Hepatitis B e Antigens,
pubmed-meshheading:1781002-Humans,
pubmed-meshheading:1781002-Infant,
pubmed-meshheading:1781002-Infant, Newborn,
pubmed-meshheading:1781002-Male,
pubmed-meshheading:1781002-Middle Aged,
pubmed-meshheading:1781002-Singapore
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pubmed:articleTitle |
Horizontal or vertical transmission of hepatitis B virus? A serological survey in family members of hepatitis B carriers in Singapore.
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pubmed:affiliation |
Department of Medicine, National University Hospital, Singapore.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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