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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2008-2-4
pubmed:abstractText
The purpose of this study was to evaluate chest CTA protocol using retrospective ECG-gating and triphasic IV contrast regimen for comprehensive evaluation of patients with acute non-specific chest pain. ECG-triggered dose modulation was used with a 64-MDCT scanner in 56 non-critically ill patients with acute nonspecific chest pain using triphasic IV regimen: 50 ml contrast followed by 50 ml 60% contrast/saline and 30 ml normal saline. Lungs, aorta, pulmonary and coronary arteries were graded on a 5-point scale (5, best). Aorta and pulmonary artery attenuation was measured and three coronary artery groups were evaluated. Comparison with invasive coronary angiography was obtained in nine patients on a per segment (16 total) basis. Dosimetry values were obtained. Studies were satisfactory in all patients (score >3). Aorta and pulmonary artery attenuation was >200 HU in 90.5%. Lung or pleura, non-cardiac vascular and coronary arteries disease were detected in 20, 11 and 16 patients, respectively. Median coronary angiography (grade 5) was significantly higher than acceptable for diagnosis grade 4 (p < 0.001). Per segment, weighted kappa statistic was 0.79 indicating substantial agreement with catheter angiography (p<0.001). Average DLP was 1,490 +/- 412 mGy-cm. Gated 64-MDCT angiography with triphasic IV contrast is a robust multipurpose technique for patients with acute non-specific chest pain.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0938-7994
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
308-17
pubmed:meshHeading
pubmed-meshheading:17763855-Acute Disease, pubmed-meshheading:17763855-Aortography, pubmed-meshheading:17763855-Chest Pain, pubmed-meshheading:17763855-Contrast Media, pubmed-meshheading:17763855-Coronary Angiography, pubmed-meshheading:17763855-Coronary Artery Disease, pubmed-meshheading:17763855-Electrocardiography, pubmed-meshheading:17763855-Humans, pubmed-meshheading:17763855-Lung, pubmed-meshheading:17763855-Lung Diseases, pubmed-meshheading:17763855-Middle Aged, pubmed-meshheading:17763855-Observer Variation, pubmed-meshheading:17763855-Pleural Diseases, pubmed-meshheading:17763855-Pulmonary Artery, pubmed-meshheading:17763855-Radiographic Image Enhancement, pubmed-meshheading:17763855-Sodium Chloride, pubmed-meshheading:17763855-Tomography, X-Ray Computed, pubmed-meshheading:17763855-Triiodobenzoic Acids, pubmed-meshheading:17763855-Vascular Diseases
pubmed:year
2008
pubmed:articleTitle
ECG-gated chest CT angiography with 64-MDCT and tri-phasic IV contrast administration regimen in patients with acute non-specific chest pain.
pubmed:affiliation
Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA. dlitmano@bidmc.harvard.edu
pubmed:publicationType
Journal Article, Evaluation Studies