| pubmed-article:17761533 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17761533 | lifeskim:mentions | umls-concept:C0026845 | lld:lifeskim |
| pubmed-article:17761533 | lifeskim:mentions | umls-concept:C1334343 | lld:lifeskim |
| pubmed-article:17761533 | lifeskim:mentions | umls-concept:C2246365 | lld:lifeskim |
| pubmed-article:17761533 | lifeskim:mentions | umls-concept:C0162610 | lld:lifeskim |
| pubmed-article:17761533 | lifeskim:mentions | umls-concept:C1704666 | lld:lifeskim |
| pubmed-article:17761533 | lifeskim:mentions | umls-concept:C1517892 | lld:lifeskim |
| pubmed-article:17761533 | lifeskim:mentions | umls-concept:C0208973 | lld:lifeskim |
| pubmed-article:17761533 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:17761533 | pubmed:dateCreated | 2007-10-26 | lld:pubmed |
| pubmed-article:17761533 | pubmed:abstractText | By yeast two-hybrid screening, we found three novel interactors (UNC-95, LIM-8, and LIM-9) for UNC-97/PINCH in Caenorhabditis elegans. All three proteins contain LIM domains that are required for binding. Among the three interactors, LIM-8 and LIM-9 also bind to UNC-96, a component of sarcomeric M-lines. UNC-96 and LIM-8 also bind to the C-terminal portion of a myosin heavy chain (MHC), MHC A, which resides in the middle of thick filaments in the proximity of M-lines. All interactions identified by yeast two-hybrid assays were confirmed by in vitro binding assays using purified proteins. All three novel UNC-97 interactors are expressed in body wall muscle and by antibodies localize to M-lines. Either a decreased or an increased dosage of UNC-96 results in disorganization of thick filaments. Our previous studies showed that UNC-98, a C2H2 Zn finger protein, acts as a linkage between UNC-97, an integrin-associated protein, and MHC A in myosin thick filaments. In this study, we demonstrate another mechanism by which this linkage occurs: from UNC-97 through LIM-8 or LIM-9/UNC-96 to myosin. | lld:pubmed |
| pubmed-article:17761533 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17761533 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17761533 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17761533 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17761533 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:17761533 | pubmed:issn | 1059-1524 | lld:pubmed |
| pubmed-article:17761533 | pubmed:author | pubmed-author:KaibuchiKozoK | lld:pubmed |
| pubmed-article:17761533 | pubmed:author | pubmed-author:QadotaHiroshi... | lld:pubmed |
| pubmed-article:17761533 | pubmed:author | pubmed-author:MercerKristin... | lld:pubmed |
| pubmed-article:17761533 | pubmed:author | pubmed-author:BenianGuy MGM | lld:pubmed |
| pubmed-article:17761533 | pubmed:author | pubmed-author:MillerRachel... | lld:pubmed |
| pubmed-article:17761533 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17761533 | pubmed:volume | 18 | lld:pubmed |
| pubmed-article:17761533 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17761533 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17761533 | pubmed:pagination | 4317-26 | lld:pubmed |
| pubmed-article:17761533 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:17761533 | pubmed:meshHeading | pubmed-meshheading:17761533... | lld:pubmed |
| pubmed-article:17761533 | pubmed:meshHeading | pubmed-meshheading:17761533... | lld:pubmed |
| pubmed-article:17761533 | pubmed:meshHeading | pubmed-meshheading:17761533... | lld:pubmed |
| pubmed-article:17761533 | pubmed:meshHeading | pubmed-meshheading:17761533... | lld:pubmed |
| pubmed-article:17761533 | pubmed:meshHeading | pubmed-meshheading:17761533... | lld:pubmed |
| pubmed-article:17761533 | pubmed:meshHeading | pubmed-meshheading:17761533... | lld:pubmed |
| pubmed-article:17761533 | pubmed:meshHeading | pubmed-meshheading:17761533... | lld:pubmed |
| pubmed-article:17761533 | pubmed:meshHeading | pubmed-meshheading:17761533... | lld:pubmed |
| pubmed-article:17761533 | pubmed:meshHeading | pubmed-meshheading:17761533... | lld:pubmed |
| pubmed-article:17761533 | pubmed:meshHeading | pubmed-meshheading:17761533... | lld:pubmed |
| pubmed-article:17761533 | pubmed:meshHeading | pubmed-meshheading:17761533... | lld:pubmed |
| pubmed-article:17761533 | pubmed:meshHeading | pubmed-meshheading:17761533... | lld:pubmed |
| pubmed-article:17761533 | pubmed:meshHeading | pubmed-meshheading:17761533... | lld:pubmed |
| pubmed-article:17761533 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17761533 | pubmed:articleTitle | Two LIM domain proteins and UNC-96 link UNC-97/pinch to myosin thick filaments in Caenorhabditis elegans muscle. | lld:pubmed |
| pubmed-article:17761533 | pubmed:affiliation | Department of Pathology, Emory University, Atlanta, GA 30322, USA. | lld:pubmed |
| pubmed-article:17761533 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17761533 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:17761533 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| entrez-gene:173301 | entrezgene:pubmed | pubmed-article:17761533 | lld:entrezgene |
| entrez-gene:175831 | entrezgene:pubmed | pubmed-article:17761533 | lld:entrezgene |
| entrez-gene:175952 | entrezgene:pubmed | pubmed-article:17761533 | lld:entrezgene |
| entrez-gene:177482 | entrezgene:pubmed | pubmed-article:17761533 | lld:entrezgene |
| entrez-gene:179676 | entrezgene:pubmed | pubmed-article:17761533 | lld:entrezgene |
| entrez-gene:179808 | entrezgene:pubmed | pubmed-article:17761533 | lld:entrezgene |
| entrez-gene:180827 | entrezgene:pubmed | pubmed-article:17761533 | lld:entrezgene |
| entrez-gene:3565712 | entrezgene:pubmed | pubmed-article:17761533 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:17761533 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:17761533 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:17761533 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:17761533 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:17761533 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17761533 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17761533 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17761533 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17761533 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17761533 | lld:pubmed |
