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rdf:type |
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lifeskim:mentions |
umls-concept:C0205217,
umls-concept:C0334227,
umls-concept:C0376358,
umls-concept:C0392756,
umls-concept:C0441655,
umls-concept:C0598934,
umls-concept:C0599697,
umls-concept:C1366526,
umls-concept:C1418388,
umls-concept:C1515655,
umls-concept:C1704928
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pubmed:dateCreated |
2007-9-12
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pubmed:abstractText |
Induction of apoptosis is one strategy for treatment of prostate cancer. The Shb adapter protein has been found to regulate apoptosis in various cell types and consequently human prostate cancer 3 (PC3) cells were transfected to obtain cells overexpressing Shb in order to increase our understanding of the mechanisms regulating PC3 cell apoptosis.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-10391251,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-10404514,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-10464310,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-10637231,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-10713049,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-10828022,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-10964922,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-11014196,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-11057897,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-11095946,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-12167702,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-12195027,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-12417302,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-12589052,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-12726862,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-12776987,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-12807754,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-1327520,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-14708008,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-14747051,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-15464388,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-15617027,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-15695396,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-15708859,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-15891014,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-16110748,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-16374544,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-17031491,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-17112510,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-7511798,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-7537362,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-7651539,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-8171020,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-8806685,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-9315092,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17697368-9484780
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2-methoxyestradiol,
http://linkedlifedata.com/resource/pubmed/chemical/Adaptor Proteins, Signal Transducing,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Estradiol,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-abl,
http://linkedlifedata.com/resource/pubmed/chemical/SHB protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Tubulin Modulators,
http://linkedlifedata.com/resource/pubmed/chemical/p38 Mitogen-Activated Protein...
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2407
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
161
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17697368-Adaptor Proteins, Signal Transducing,
pubmed-meshheading:17697368-Animals,
pubmed-meshheading:17697368-Apoptosis,
pubmed-meshheading:17697368-Blotting, Western,
pubmed-meshheading:17697368-Cell Proliferation,
pubmed-meshheading:17697368-Enzyme Inhibitors,
pubmed-meshheading:17697368-Estradiol,
pubmed-meshheading:17697368-Female,
pubmed-meshheading:17697368-Humans,
pubmed-meshheading:17697368-Male,
pubmed-meshheading:17697368-Mice,
pubmed-meshheading:17697368-Mice, Nude,
pubmed-meshheading:17697368-Prostatic Neoplasms,
pubmed-meshheading:17697368-Proto-Oncogene Proteins,
pubmed-meshheading:17697368-Proto-Oncogene Proteins c-abl,
pubmed-meshheading:17697368-Signal Transduction,
pubmed-meshheading:17697368-Transfection,
pubmed-meshheading:17697368-Tubulin Modulators,
pubmed-meshheading:17697368-Tumor Cells, Cultured,
pubmed-meshheading:17697368-Up-Regulation,
pubmed-meshheading:17697368-p38 Mitogen-Activated Protein Kinases
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pubmed:year |
2007
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pubmed:articleTitle |
Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein.
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pubmed:affiliation |
Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden. padideh.davoodpour@ki.se <padideh.davoodpour@ki.se>
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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