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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-8-13
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pubmed:abstractText |
A new series of salicylanilide acetates was synthesized and evaluated for their in vitro antifungal and antituberculotic activity. Some of the evaluated compounds possessed comparable or better antifungal activity than a fluconazole standard. All these compounds exhibited very good potential and their in vitro activity against drug resistant and sensitive clinical isolates of Mycobacteria were found to be equivalent or better than a standard of isoniazide, a well-known first-line drug for tuberculosis treatment.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1420-3049
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-12
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pubmed:dateRevised |
2009-10-27
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pubmed:meshHeading |
pubmed-meshheading:17693949-Anti-Bacterial Agents,
pubmed-meshheading:17693949-Antifungal Agents,
pubmed-meshheading:17693949-Candida albicans,
pubmed-meshheading:17693949-Cell Line,
pubmed-meshheading:17693949-Cell Survival,
pubmed-meshheading:17693949-Fluconazole,
pubmed-meshheading:17693949-Humans,
pubmed-meshheading:17693949-Microbial Sensitivity Tests,
pubmed-meshheading:17693949-Microbial Viability,
pubmed-meshheading:17693949-Molecular Structure,
pubmed-meshheading:17693949-Mycobacterium,
pubmed-meshheading:17693949-Salicylanilides,
pubmed-meshheading:17693949-Structure-Activity Relationship
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pubmed:year |
2007
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pubmed:articleTitle |
Salicylanilide acetates: synthesis and antibacterial evaluation.
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pubmed:affiliation |
Faculty of Pharmacy in Hradec Kralove, Charles University in Prague, Heyrovskeho 1203, Hradec Kralove, Czech Republic. jarmila.vinsova@faf.cuni.cz
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pubmed:publicationType |
Journal Article
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