Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-8-7
pubmed:abstractText
The cardiometabolic syndrome (CMS) and diabetes are associated with higher cardiovascular risk. The authors compared the association of CMS risk factors and diabetes with coronary and aortic calcium. A total of 4468 adults (42% female) underwent computed tomography for determination of coronary artery calcium (CAC) and thoracic aortic calcium (TAC) and were classified according to the presence of diabetes mellitus (DM) and number of CMS risk factors. The prevalence of CAC ranged from 51% in men and 35% in women with neither DM nor CMS to 75% in men and 58% in women with both DM and CMS, whereas TAC ranged from 29% to 44% in men and 36% to 55% in women. Women with four or five CMS risk factors more often had CAC (53%) and TAC (51%) than those with DM without CMS (40% and 35%, respectively) (p<0.001 across all disease groups). Adjusted odds (and 95% confidence intervals) of CAC for those with three CMS risk factors, four CMS risk factors, DM without CMS, and DM with CMS vs. those without CMS were 1.14 (0.93-1.39), 1.46 (1.12-1.90), 1.59 (1.06-2.38), and 2.10 (1.52-2.90) for CAC and 1.14 (0.91-1.42), 1.03 (0.77-1.37), 1.03 (0.68-1.54), and 1.41 (1.03-1.92) for TAC. Multiple CMS risk factors are associated with increased CAC, but not TAC; DM with CMS has the highest prevalence of CAC and TAC.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1559-4564
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
90-4
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:17679823-Adult, pubmed-meshheading:17679823-Aged, pubmed-meshheading:17679823-Aged, 80 and over, pubmed-meshheading:17679823-Aorta, Thoracic, pubmed-meshheading:17679823-Atherosclerosis, pubmed-meshheading:17679823-Calcinosis, pubmed-meshheading:17679823-Coronary Artery Disease, pubmed-meshheading:17679823-Diabetes Complications, pubmed-meshheading:17679823-Female, pubmed-meshheading:17679823-Humans, pubmed-meshheading:17679823-Logistic Models, pubmed-meshheading:17679823-Male, pubmed-meshheading:17679823-Metabolic Syndrome X, pubmed-meshheading:17679823-Middle Aged, pubmed-meshheading:17679823-Odds Ratio, pubmed-meshheading:17679823-Prevalence, pubmed-meshheading:17679823-Risk Assessment, pubmed-meshheading:17679823-Risk Factors, pubmed-meshheading:17679823-Severity of Illness Index, pubmed-meshheading:17679823-Tomography, X-Ray Computed
pubmed:year
2006
pubmed:articleTitle
Comparison of atherosclerotic calcification burden in persons with the cardiometabolic syndrome and diabetes.
pubmed:affiliation
Department of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't