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pubmed-article:17606729pubmed:abstractTextGiven the complex tumor microenvironment, targeting multiple cellular components may be the most effective cancer treatment strategy. Therefore, we tested whether antiangiogenic and immune-based therapy might synergize by characterizing the activity of DC101, an antiangiogenic monoclonal antibody specific for vascular endothelial growth factor receptor-2 (VEGF-R2), alone and with HER-2/neu (neu)-targeted vaccination.lld:pubmed
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pubmed-article:17606729pubmed:articleTitleA vascular endothelial growth factor receptor-2 inhibitor enhances antitumor immunity through an immune-based mechanism.lld:pubmed
pubmed-article:17606729pubmed:affiliationThe Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.lld:pubmed
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