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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
13
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pubmed:dateCreated |
2007-7-3
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|
pubmed:abstractText |
Given the complex tumor microenvironment, targeting multiple cellular components may be the most effective cancer treatment strategy. Therefore, we tested whether antiangiogenic and immune-based therapy might synergize by characterizing the activity of DC101, an antiangiogenic monoclonal antibody specific for vascular endothelial growth factor receptor-2 (VEGF-R2), alone and with HER-2/neu (neu)-targeted vaccination.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Jul
|
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pubmed:issn |
1078-0432
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
13
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
3951-9
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pubmed:dateRevised |
2011-7-29
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pubmed:meshHeading |
pubmed-meshheading:17606729-Angiogenesis Inhibitors,
pubmed-meshheading:17606729-Animals,
pubmed-meshheading:17606729-Antibodies, Monoclonal,
pubmed-meshheading:17606729-Antigen Presentation,
pubmed-meshheading:17606729-Antineoplastic Agents,
pubmed-meshheading:17606729-CD8-Positive T-Lymphocytes,
pubmed-meshheading:17606729-Cancer Vaccines,
pubmed-meshheading:17606729-Cell Line, Tumor,
pubmed-meshheading:17606729-Flow Cytometry,
pubmed-meshheading:17606729-Humans,
pubmed-meshheading:17606729-Immune System,
pubmed-meshheading:17606729-Lymphocytes, Tumor-Infiltrating,
pubmed-meshheading:17606729-Mice,
pubmed-meshheading:17606729-Neovascularization, Pathologic,
pubmed-meshheading:17606729-Vascular Endothelial Growth Factor Receptor-2
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pubmed:year |
2007
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|
pubmed:articleTitle |
A vascular endothelial growth factor receptor-2 inhibitor enhances antitumor immunity through an immune-based mechanism.
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pubmed:affiliation |
The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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