Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1992-2-12
pubmed:abstractText
Viral haemorrhagic disease (VHD) is a new and severe infectious disease of rabbits, with a high rate of morbidity and mortality. The disease occurs throughout the year, affecting only adult rabbits and not other domestic animals, fowls or laboratory rodents. The transmission is horizontal, by direct or indirect contact, and through all routes. There is no evidence of congenital infection or biological vectors. The causative agent, viral haemorrhagic disease virus (VHDV), is present in all tissues, excretions and secretions. It is an icosahedral and nonenveloped parvo-like virus. The genome, as determined by classical methods, high performance chromatography and in vitro synthesis of double-stranded DNA, is linear, single-stranded DNA. VHDV can agglutinate human erythrocytes at very high titres, irrespective of blood groups, and has a stable reaction to many physical and chemical factors. VHDV has been adapted to grow on rabbit kidney cell strain (DJRK) culture and to produce cytopathic effect (CPE). Inactivated cell culture can protect inoculated rabbits against virulent VHDV. The disease is now effectively controlled in the People's Republic of China, but has not yet been completely eradicated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0253-1933
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
393-408
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Viral haemorrhagic disease of rabbits in the People's Republic of China: epidemiology and virus characterisation.
pubmed:affiliation
Department of Veterinary Science, Nanjing Agricultural University, Jiangsu Province, People's Republic of China.
pubmed:publicationType
Journal Article, Review