Linked Life Data

17589307

Source:http://linkedlifedata.com/resource/pubmed/id/17589307

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2007-6-25
pubmed:abstractText
We analyzed, with a new imaging technique, the rapid axon reflex flare responses in human skin upon transcutaneous delivery of electrical stimuli at 1, 5, 10 and 50 Hz in single bursts of five pulses each. Two-dimensional perfusion images covering an area of 8 x 8 cm(2) were captured at 25 Hz and their averages saved at 0.5 Hz. The stimulation caused an axon reflex flare (maximum 3 cm(2), 20 s after stimulation) that gradually resolved within 2 min. Maximum flare responses developed at 5 Hz, whereas pain ratings increased with stimulation frequency. The highest neuropeptide release at 5 Hz correlates to the discharge characteristics of mechanoinsensitive C-fibers, whereas the maximum pain intensity at 50 Hz may be attributed to the activation of A-delta fibers.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0959-4965
pubmed:author
pubmed:issnType
Print
pubmed:day
16
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1101-5
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Rapid flare development evoked by current frequency-dependent stimulation analyzed by full-field laser perfusion imaging.
pubmed:affiliation
Department of Anaesthesiology and Intensive Care Medicine, Medical Faculty Mannheim, University of Heidelberg, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't