Source:http://linkedlifedata.com/resource/pubmed/id/17498420
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2007-5-14
|
| pubmed:abstractText |
Recurrent aphthous stomatitis (RAS) is a common ulcerative condition of the oral mucosa. We assessed minocycline and tetracycline oral rinses in patients with frequent episodes of RAS in a clinical randomized crossover trial. Seventeen patients with high frequency recurrent minor RAS were randomly allocated to a cross-over topical therapy with 0.2 percent minocycline or 0.25 percent tetracycline aqueous solution mouthwash. The minimum interval between the cross-over was 30 days. The intensity of pain was recorded daily using a visual analogue scale. Minocycline mouthwashes as compared to topical tetracycline rinses resulted in significantly improved pain control, by reducing the severity and duration of pain. Topical minocycline rinse may be a potential treatment for other mucosal diseases that result in mucosal ulceration and pain.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
1087-2108
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
13
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1
|
| pubmed:meshHeading |
pubmed-meshheading:17498420-Administration, Topical,
pubmed-meshheading:17498420-Adolescent,
pubmed-meshheading:17498420-Adult,
pubmed-meshheading:17498420-Aged,
pubmed-meshheading:17498420-Cross-Over Studies,
pubmed-meshheading:17498420-Female,
pubmed-meshheading:17498420-Humans,
pubmed-meshheading:17498420-Male,
pubmed-meshheading:17498420-Middle Aged,
pubmed-meshheading:17498420-Minocycline,
pubmed-meshheading:17498420-Mouth Mucosa,
pubmed-meshheading:17498420-Mouthwashes,
pubmed-meshheading:17498420-Pain Measurement,
pubmed-meshheading:17498420-Patient Satisfaction,
pubmed-meshheading:17498420-Recurrence,
pubmed-meshheading:17498420-Risk Assessment,
pubmed-meshheading:17498420-Severity of Illness Index,
pubmed-meshheading:17498420-Stomatitis, Aphthous,
pubmed-meshheading:17498420-Tetracycline,
pubmed-meshheading:17498420-Treatment Outcome
|
| pubmed:year |
2007
|
| pubmed:articleTitle |
Topical minocycline and tetracycline rinses in treatment of recurrent aphthous stomatitis: a randomized cross-over study.
|
| pubmed:affiliation |
Department of Oral Pathology and Oral Medicine, the Maurice and Gabriella Goldschleger School of Dental Medicine, Tel Aviv University, Israel.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial
|