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pubmed-article:17472992pubmed:abstractTextEndothelin receptor antagonism has become an important component in the treatment of pulmonary arterial hypertension (PAH) associated with connective tissue disease (CTD). The purpose of this study was to analyse the safety and effectiveness of sitaxsentan, a selective antagonist of the ET(A) receptor, in a cohort of patients with PAH and CTD. Short-term clinical and haemodynamic effects and longer-term follow-up data are presented.lld:pubmed
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pubmed-article:17472992pubmed:articleTitleSelective endothelin A receptor antagonism with sitaxsentan for pulmonary arterial hypertension associated with connective tissue disease.lld:pubmed
pubmed-article:17472992pubmed:affiliationJohns Hopkins University, School of Medicine, Baltimore, Maryland, USA.lld:pubmed
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