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rdf:type |
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lifeskim:mentions |
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0030705,
umls-concept:C0036980,
umls-concept:C0132555,
umls-concept:C0155626,
umls-concept:C0205322,
umls-concept:C0205390,
umls-concept:C1274040,
umls-concept:C1280500,
umls-concept:C1522701,
umls-concept:C2603343
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pubmed:issue |
9
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pubmed:dateCreated |
2007-5-7
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pubmed:abstractText |
Previous studies suggested haemodynamic benefits and, possibly, mortality reduction with the use of nitric oxide synthase (NOS) inhibition in patients with acute myocardial infarction (AMI) complicated by cardiogenic shock (CS). We assessed preliminary efficacy and safety of four doses of l-n-monomethyl-arginine (l-NMMA), a non-selective NOS inhibitor, in patients with AMI complicated by CS despite an open infarct-related artery.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0195-668X
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pubmed:author |
pubmed-author:AlexanderJohn HJH,
pubmed-author:BaranDavid ADA,
pubmed-author:BullerChristopher ECE,
pubmed-author:CantorWarren JWJ,
pubmed-author:CotterGadG,
pubmed-author:DzavíkVladimirV,
pubmed-author:FarkouhMichael EME,
pubmed-author:GrossSteven SSS,
pubmed-author:HarringtonRobert ARA,
pubmed-author:HathawayDavidD,
pubmed-author:HazenStanley LSL,
pubmed-author:HochmanJudith SJS,
pubmed-author:HolmesDavid RDR,
pubmed-author:KleimanNeal SNS,
pubmed-author:OhmanE MagnusEM,
pubmed-author:PanzaJulio AJA,
pubmed-author:ParrilloJoseph EJE,
pubmed-author:ProndzinskyRolandR,
pubmed-author:RamanathanKrishnanK,
pubmed-author:ReynoldsHarmony RHR,
pubmed-author:SHould we inhibit nitric Oxide synthase in Cardiogenic shocK 2...,
pubmed-author:StebbinsAmanda LAL,
pubmed-author:VeredZviZ,
pubmed-author:WebbJohn GJG
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1109-16
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pubmed:dateRevised |
2010-12-3
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pubmed:meshHeading |
pubmed-meshheading:17459901-Aged,
pubmed-meshheading:17459901-Enzyme Inhibitors,
pubmed-meshheading:17459901-Female,
pubmed-meshheading:17459901-Hemodynamics,
pubmed-meshheading:17459901-Humans,
pubmed-meshheading:17459901-Infusions, Intravenous,
pubmed-meshheading:17459901-Male,
pubmed-meshheading:17459901-Myocardial Infarction,
pubmed-meshheading:17459901-Nitric Oxide Synthase,
pubmed-meshheading:17459901-Shock, Cardiogenic,
pubmed-meshheading:17459901-omega-N-Methylarginine
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pubmed:year |
2007
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pubmed:articleTitle |
Effect of nitric oxide synthase inhibition on haemodynamics and outcome of patients with persistent cardiogenic shock complicating acute myocardial infarction: a phase II dose-ranging study.
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pubmed:affiliation |
University Health Network, Toronto General Hospital, 6-246, 200 Elizabeth Street, Toronto M5G 2C4, Ontario, Canada. vlad.dzavik@uhn.on.ca
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase II,
Research Support, N.I.H., Extramural
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