Linked Life Data

17450502

Source:http://linkedlifedata.com/resource/pubmed/id/17450502

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2007-7-30
pubmed:abstractText
Two limonoids were isolated from the methanol extract of Khaya senegalensis (Meliaceae), and their structures were identified as 3alpha,7alpha-dideacetylkhivorin (1) and 1-O-acetylkhayanolide B (2) on the basis of MS and NMR spectral data. Complete assignments of (1)H and (13)C chemical shifts for compounds 1 and 2 were achieved by means of 1D and 2D NMR including DEPT, (1)H-(1)H COSY, HMQC, HMBC experiments. Compound 1 showed significant growth inhibitory activities against MCF-7, SiHa and Caco-2 cells with IC(50) values in the range of 0.07-0.14 microm (35-69 ppm) while compound 2 did not.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0951-418X
pubmed:author
pubmed:copyrightInfo
(c) 2007 John Wiley & Sons, Ltd.
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
731-4
pubmed:dateRevised
2007-12-3
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Anticancer activity of limonoid from Khaya senegalensis.
pubmed:affiliation
Department of Food Science and Human Nutrition, Clemson University, Clemson, SC 29634, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural