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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6-7
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pubmed:dateCreated |
2007-7-6
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pubmed:abstractText |
The interferon (IFN) system is a major effector of the innate immunity that allows time for the subsequent establishment of an adaptive immune response against wide-range pathogens. The effectiveness of IFN to control initial infection requires the cooperation between several pathways induced in the target cells. Recent studies that highlight the implication of the 3'-5' exonuclease ISG20 (IFN Stimulated Gene product of 20 kDa) in the host's defenses against pathogens are summarised in this review.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0300-9084
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
831-5
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17445960-Amino Acid Sequence,
pubmed-meshheading:17445960-Animals,
pubmed-meshheading:17445960-Cell Line,
pubmed-meshheading:17445960-Exonucleases,
pubmed-meshheading:17445960-Humans,
pubmed-meshheading:17445960-Immunity, Innate,
pubmed-meshheading:17445960-Inflammation,
pubmed-meshheading:17445960-Interferons,
pubmed-meshheading:17445960-Models, Biological,
pubmed-meshheading:17445960-Molecular Sequence Data,
pubmed-meshheading:17445960-RNA, Small Interfering,
pubmed-meshheading:17445960-RNA Viruses,
pubmed-meshheading:17445960-Toll-Like Receptors
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pubmed:articleTitle |
ISG20, an actor of the innate immune response.
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pubmed:affiliation |
UMR5160 CNRS, EFS, 240 Avenue Emile Jeanbrau, 34094 Montpellier Cedex 5, France.
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pubmed:publicationType |
Journal Article
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