pubmed-article:17444626 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:17444626 | lifeskim:mentions | umls-concept:C0003402 | lld:lifeskim |
pubmed-article:17444626 | lifeskim:mentions | umls-concept:C0003209 | lld:lifeskim |
pubmed-article:17444626 | lifeskim:mentions | umls-concept:C0023791 | lld:lifeskim |
pubmed-article:17444626 | lifeskim:mentions | umls-concept:C0596040 | lld:lifeskim |
pubmed-article:17444626 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
pubmed-article:17444626 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
pubmed-article:17444626 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
pubmed-article:17444626 | lifeskim:mentions | umls-concept:C1707689 | lld:lifeskim |
pubmed-article:17444626 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
pubmed-article:17444626 | pubmed:issue | 10 | lld:pubmed |
pubmed-article:17444626 | pubmed:dateCreated | 2007-5-10 | lld:pubmed |
pubmed-article:17444626 | pubmed:abstractText | A series of N-substituted-quinolinone-3-aminoamides and their hybrids containing the alpha-lipoic acid functionality were designed and synthesized as potential bifunctional agents combining antioxidant and anti-inflammatory activity. The new compounds were evaluated for their antioxidant activity and for their ability to inhibit in vitro lipoxygenase as well as for their anti-inflammatory activity in vivo. In general, the derivatives were found to be potent antioxidant or anti-inflammatory agents. The results are discussed in terms of structure-activity relationships and an attempt is made to define the structural features required for activity. | lld:pubmed |
pubmed-article:17444626 | pubmed:language | eng | lld:pubmed |
pubmed-article:17444626 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17444626 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:17444626 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17444626 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17444626 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17444626 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17444626 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17444626 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17444626 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17444626 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17444626 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17444626 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17444626 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17444626 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17444626 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17444626 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:17444626 | pubmed:month | May | lld:pubmed |
pubmed-article:17444626 | pubmed:issn | 0022-2623 | lld:pubmed |
pubmed-article:17444626 | pubmed:author | pubmed-author:Hadjipavlou-L... | lld:pubmed |
pubmed-article:17444626 | pubmed:author | pubmed-author:DetsiAnastasi... | lld:pubmed |
pubmed-article:17444626 | pubmed:author | pubmed-author:KoufakiMariaM | lld:pubmed |
pubmed-article:17444626 | pubmed:author | pubmed-author:KontogiorgisC... | lld:pubmed |
pubmed-article:17444626 | pubmed:author | pubmed-author:Igglessi-Mark... | lld:pubmed |
pubmed-article:17444626 | pubmed:author | pubmed-author:MelagrakiGeor... | lld:pubmed |
pubmed-article:17444626 | pubmed:author | pubmed-author:AfantitisAntr... | lld:pubmed |
pubmed-article:17444626 | pubmed:author | pubmed-author:BouloumbasiDi... | lld:pubmed |
pubmed-article:17444626 | pubmed:author | pubmed-author:ProusisKyriak... | lld:pubmed |
pubmed-article:17444626 | pubmed:author | pubmed-author:AthanasellisG... | lld:pubmed |
pubmed-article:17444626 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:17444626 | pubmed:day | 17 | lld:pubmed |
pubmed-article:17444626 | pubmed:volume | 50 | lld:pubmed |
pubmed-article:17444626 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:17444626 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:17444626 | pubmed:pagination | 2450-8 | lld:pubmed |
pubmed-article:17444626 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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pubmed-article:17444626 | pubmed:year | 2007 | lld:pubmed |
pubmed-article:17444626 | pubmed:articleTitle | Design and synthesis of novel quinolinone-3-aminoamides and their alpha-lipoic acid adducts as antioxidant and anti-inflammatory agents. | lld:pubmed |
pubmed-article:17444626 | pubmed:affiliation | Laboratory of Organic Chemistry, School of Chemical Engineering, National Technical University of Athens, Zorgafou Campus, GR 157 73, Athens, Greece. adetsi@chemeng.ntua.gr | lld:pubmed |
pubmed-article:17444626 | pubmed:publicationType | Journal Article | lld:pubmed |
http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:17444626 | lld:chembl |