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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2008-8-18
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pubmed:abstractText |
A recent scan of single nucleotide polymorphisms (SNPs) on chromosome 10q found significant association of six correlated SNPs with late-onset Alzheimer's disease (AD) among Japanese. We examined the SNP with the highest statistical significance (rs3740058) in a large Caucasian American case-control cohort and the remaining five SNPs in a smaller subset of cases and controls. We observed no association of statistical significance in either the total sample or the APOE*4 non-carriers for any of the SNPs.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1558-1497
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1602-4
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:17442457-Alzheimer Disease,
pubmed-meshheading:17442457-Apolipoprotein E4,
pubmed-meshheading:17442457-Brain,
pubmed-meshheading:17442457-Case-Control Studies,
pubmed-meshheading:17442457-Chromosomes, Human, Pair 10,
pubmed-meshheading:17442457-Cohort Studies,
pubmed-meshheading:17442457-Cytoskeletal Proteins,
pubmed-meshheading:17442457-DNA Mutational Analysis,
pubmed-meshheading:17442457-European Continental Ancestry Group,
pubmed-meshheading:17442457-Gene Frequency,
pubmed-meshheading:17442457-Genetic Predisposition to Disease,
pubmed-meshheading:17442457-Genetic Testing,
pubmed-meshheading:17442457-Genotype,
pubmed-meshheading:17442457-Heterozygote,
pubmed-meshheading:17442457-Humans,
pubmed-meshheading:17442457-Polymorphism, Single Nucleotide
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pubmed:year |
2008
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pubmed:articleTitle |
No association of dynamin binding protein (DNMBP) gene SNPs and Alzheimer's disease.
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pubmed:affiliation |
Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA 15261, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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