| pubmed-article:17439326 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17439326 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:17439326 | lifeskim:mentions | umls-concept:C0442805 | lld:lifeskim |
| pubmed-article:17439326 | lifeskim:mentions | umls-concept:C0086860 | lld:lifeskim |
| pubmed-article:17439326 | lifeskim:mentions | umls-concept:C1882417 | lld:lifeskim |
| pubmed-article:17439326 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:17439326 | pubmed:dateCreated | 2007-4-18 | lld:pubmed |
| pubmed-article:17439326 | pubmed:abstractText | Reticulocyte-type 15-lipoxygenase-1 (ALOX15) has anti-inflammatory and inflammatory effects and is implicated in the development of asthma, arthritis and atherosclerosis. Previously, we screened the human ALOX15 gene for variations because genetic variability in ALOX15 might influence these diseases. We found a C>T substitution at position c.-292 in the ALOX15 promoter that created a novel binding site for the transcription factor SPI1 and increased ALOX15 mRNA levels in monocytes from c.-292CT heterozygous volunteers. | lld:pubmed |
| pubmed-article:17439326 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17439326 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17439326 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17439326 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17439326 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17439326 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17439326 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17439326 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17439326 | pubmed:issn | 1434-6621 | lld:pubmed |
| pubmed-article:17439326 | pubmed:author | pubmed-author:MosandlArminA | lld:pubmed |
| pubmed-article:17439326 | pubmed:author | pubmed-author:HersbergerMar... | lld:pubmed |
| pubmed-article:17439326 | pubmed:author | pubmed-author:MuntwylerJörg... | lld:pubmed |
| pubmed-article:17439326 | pubmed:author | pubmed-author:WittwerJonasJ | lld:pubmed |
| pubmed-article:17439326 | pubmed:author | pubmed-author:BayerMathiasM | lld:pubmed |
| pubmed-article:17439326 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17439326 | pubmed:volume | 45 | lld:pubmed |
| pubmed-article:17439326 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17439326 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17439326 | pubmed:pagination | 487-92 | lld:pubmed |
| pubmed-article:17439326 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:17439326 | pubmed:meshHeading | pubmed-meshheading:17439326... | lld:pubmed |
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| pubmed-article:17439326 | pubmed:meshHeading | pubmed-meshheading:17439326... | lld:pubmed |
| pubmed-article:17439326 | pubmed:meshHeading | pubmed-meshheading:17439326... | lld:pubmed |
| pubmed-article:17439326 | pubmed:meshHeading | pubmed-meshheading:17439326... | lld:pubmed |
| pubmed-article:17439326 | pubmed:meshHeading | pubmed-meshheading:17439326... | lld:pubmed |
| pubmed-article:17439326 | pubmed:meshHeading | pubmed-meshheading:17439326... | lld:pubmed |
| pubmed-article:17439326 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17439326 | pubmed:articleTitle | The c.-292C>T promoter polymorphism increases reticulocyte-type 15-lipoxygenase-1 activity and could be atheroprotective. | lld:pubmed |
| pubmed-article:17439326 | pubmed:affiliation | Institute of Clinical Chemistry, Center for Integrative Human Physiology, University Hospital Zurich, Zurich, Switzerland. | lld:pubmed |
| pubmed-article:17439326 | pubmed:publicationType | Journal Article | lld:pubmed |
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