rdf:type |
|
lifeskim:mentions |
umls-concept:C0006142,
umls-concept:C0027996,
umls-concept:C0035527,
umls-concept:C0056077,
umls-concept:C0232970,
umls-concept:C0443602,
umls-concept:C1280500,
umls-concept:C1514811,
umls-concept:C1516213,
umls-concept:C1561577,
umls-concept:C1706462
|
pubmed:issue |
9-10
|
pubmed:dateCreated |
2007-6-4
|
pubmed:abstractText |
Tamoxifen (TAM), a non-steroidal anti-estrogen that is widely used in adjuvant therapy for all stages of breast carcinomas and in chemoprevention of high-risk group. The hepatic estrogenic effect of TAM induces hypertriglyceridemia by reduced activity of lipolytic enzymes (LPL) on triglycerides. Coenzyme Q10 (Co Q10), riboflavin and niacin are proved to be potent antioxidant and protective agents against many diseases including cancer and cardiovascular diseases (CVD). In this context, the objective of the study is to find the effect of the combined modality of Co Q10 (100 mg), riboflavin (10 mg) and niacin (50 mg) with TAM (10 mg twice a day) on serum lipids and lipoprotein levels in postmenopausal women with breast cancer.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, LDL,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, VLDL,
http://linkedlifedata.com/resource/pubmed/chemical/Coenzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Niacin,
http://linkedlifedata.com/resource/pubmed/chemical/Riboflavin,
http://linkedlifedata.com/resource/pubmed/chemical/Tamoxifen,
http://linkedlifedata.com/resource/pubmed/chemical/Triglycerides,
http://linkedlifedata.com/resource/pubmed/chemical/Ubiquinone,
http://linkedlifedata.com/resource/pubmed/chemical/coenzyme Q10
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
|
pubmed:issn |
0009-9120
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
40
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
623-8
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pubmed:meshHeading |
pubmed-meshheading:17425952-Adult,
pubmed-meshheading:17425952-Aged,
pubmed-meshheading:17425952-Breast Neoplasms,
pubmed-meshheading:17425952-Cholesterol, LDL,
pubmed-meshheading:17425952-Cholesterol, VLDL,
pubmed-meshheading:17425952-Coenzymes,
pubmed-meshheading:17425952-Drug Therapy, Combination,
pubmed-meshheading:17425952-Female,
pubmed-meshheading:17425952-Humans,
pubmed-meshheading:17425952-Hyperlipidemias,
pubmed-meshheading:17425952-Lipid Metabolism,
pubmed-meshheading:17425952-Lipoproteins,
pubmed-meshheading:17425952-Middle Aged,
pubmed-meshheading:17425952-Niacin,
pubmed-meshheading:17425952-Postmenopause,
pubmed-meshheading:17425952-Riboflavin,
pubmed-meshheading:17425952-Tamoxifen,
pubmed-meshheading:17425952-Triglycerides,
pubmed-meshheading:17425952-Ubiquinone
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pubmed:year |
2007
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pubmed:articleTitle |
Ameliorating effect of coenzyme Q10, riboflavin and niacin in tamoxifen-treated postmenopausal breast cancer patients with special reference to lipids and lipoproteins.
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pubmed:affiliation |
Department of Medical Biochemistry, University of Madras, Taramani Campus, Chennai - 600 113, Tamil Nadu, India.
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pubmed:publicationType |
Journal Article
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