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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2007-2-27
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pubmed:abstractText |
It has been suggested that early menopause increases the risk of aging-macula disorder (AMD), the major cause of incurable blindness with a dry and wet late subtype, and that exposure to endogenous or postmenopausal exogenous estrogens reduces this risk. This study was undertaken to investigate whether genetic variations in the estrogen receptor alpha (ESR1) gene are associated with incident AMD.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0146-0404
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1012-7
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pubmed:meshHeading |
pubmed-meshheading:17325140-Estrogen Receptor alpha,
pubmed-meshheading:17325140-Female,
pubmed-meshheading:17325140-Genotype,
pubmed-meshheading:17325140-Haplotypes,
pubmed-meshheading:17325140-Humans,
pubmed-meshheading:17325140-Incidence,
pubmed-meshheading:17325140-Macular Degeneration,
pubmed-meshheading:17325140-Male,
pubmed-meshheading:17325140-Middle Aged,
pubmed-meshheading:17325140-Netherlands,
pubmed-meshheading:17325140-Polymerase Chain Reaction,
pubmed-meshheading:17325140-Polymorphism, Single Nucleotide,
pubmed-meshheading:17325140-Proportional Hazards Models,
pubmed-meshheading:17325140-Prospective Studies,
pubmed-meshheading:17325140-Risk Factors
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pubmed:year |
2007
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pubmed:articleTitle |
Estrogen receptor alpha gene polymorphisms associated with incident aging macula disorder.
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pubmed:affiliation |
Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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