Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2007-3-13
pubmed:abstractText
PCDDs, PCDFs, and dioxin like PCBs (dioxin) surveillance results derived from regular environmental monitoring as well as other dioxin surveys by national and local governmental bodies in Japan were collected and analyzed. Several thousand data for air and soil in fiscal year 2001 (from 01/04/2001 to 31/03/2002) and 2002, water (from the sea, rivers and lakes), sediment (from the sea, rivers and lakes), ground water, aquatic organisms, purified water from water purification plants, raw water from water purification plants, human breast milk, and human blood in fiscal 2001, and total diet study (TDS) and various kinds of foodstuff in fiscal 1998-2002 were collected. Average human uptake of dioxin in Japan in fiscal 2001 was estimated at 1.68 pg-TEQ/kg-bw/day, while uptake in fiscal 2002 was estimated at 1.52 pg-TEQ/kg-bw/day. Diet accounted for more than 90% of the total intake. Contributions of inhalation and soil ingestion were relatively small. Age-group-specific contribution of various foodstuff to total dietary intake was also estimated. The estimates of intake through fish and shellfish accounted for approximately 45-70% of total dietary intake in each age group. Monte Carlo simulation was conducted, using the data of the air and soil concentrations in fiscal 2001 and the total diet study data in fiscal 1998-2001, in order to obtain information on the variability of dioxin intake; The estimated average, median, 5th percentile and 95th percentile of the intake distribution were 1.78, 1.69, 0.95 and 2.91 pg-TEQ/kg-bw/day, respectively. This study found that the average total intake estimates in Japan in both fiscal 2001 and 2002 were estimated to be below tolerable daily intake level (TDI) defined by the Ministry of Health, Labour and Welfare, Japan (i.e. 4 pg-TEQ/kg-bw/day). The 95th percentile of the dioxin intake distributions estimated with Monte Carlo simulation using the data of the air and soil concentrations in fiscal 2001 and TDS data in fiscal 1998-2001 was also below the Japanese TDI.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0045-6535
pubmed:author
pubmed:issnType
Print
pubmed:volume
67
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S247-55
pubmed:meshHeading
pubmed-meshheading:17292450-Adolescent, pubmed-meshheading:17292450-Adult, pubmed-meshheading:17292450-Age Factors, pubmed-meshheading:17292450-Benzofurans, pubmed-meshheading:17292450-Child, pubmed-meshheading:17292450-Child, Preschool, pubmed-meshheading:17292450-Environmental Exposure, pubmed-meshheading:17292450-Environmental Pollutants, pubmed-meshheading:17292450-Food Contamination, pubmed-meshheading:17292450-Housing, pubmed-meshheading:17292450-Humans, pubmed-meshheading:17292450-Infant, pubmed-meshheading:17292450-Japan, pubmed-meshheading:17292450-Middle Aged, pubmed-meshheading:17292450-Monte Carlo Method, pubmed-meshheading:17292450-Polychlorinated Biphenyls, pubmed-meshheading:17292450-Population Surveillance, pubmed-meshheading:17292450-Risk Assessment, pubmed-meshheading:17292450-Tetrachlorodibenzodioxin, pubmed-meshheading:17292450-Time Factors
pubmed:year
2007
pubmed:articleTitle
Human intake of PCDDs, PCDFs, and dioxin like PCBs in Japan, 2001 and 2002.
pubmed:affiliation
Japan Environmental Sanitation Center, Kawasaki 210-0828, Japan.
pubmed:publicationType
Journal Article