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pubmed-article:17283363pubmed:abstractTextGenomic features including unmutated immunoglobulin variable region heavy chain (IgVH) genes, del(11q22.3), del(17p13.1), and p53 mutations have been reported to predict the clinical course and overall survival of patients with chronic lymphocytic leukemia (CLL). In addition, ZAP-70 and Bcl-2 family proteins have been explored as predictors of outcome.lld:pubmed
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pubmed-article:17283363pubmed:articleTitleComprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997.lld:pubmed
pubmed-article:17283363pubmed:affiliationEastern Cooperative Oncology Group, Division of Hematology-Oncology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA. michael.grever@osumc.edulld:pubmed
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