|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2007-2-28
|
|
pubmed:abstractText |
Genomic features including unmutated immunoglobulin variable region heavy chain (IgVH) genes, del(11q22.3), del(17p13.1), and p53 mutations have been reported to predict the clinical course and overall survival of patients with chronic lymphocytic leukemia (CLL). In addition, ZAP-70 and Bcl-2 family proteins have been explored as predictors of outcome.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
1527-7755
|
|
pubmed:author |
pubmed-author:AppelbaumFrederick RFR,
pubmed-author:ByrdJohn CJC,
pubmed-author:DewaldGordon WGW,
pubmed-author:FlinnIan WIW,
pubmed-author:GreverMichael RMR,
pubmed-author:GribbenJohn GJG,
pubmed-author:JelinekDiane FDF,
pubmed-author:KitadaShinichiS,
pubmed-author:LarsonRichard ARA,
pubmed-author:LucasDavid MDM,
pubmed-author:NeubergDonna SDS,
pubmed-author:PaiettaElisabethE,
pubmed-author:ReedJohn CJC,
pubmed-author:TallmanMartin SMS
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
1
|
|
pubmed:volume |
25
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
799-804
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:17283363-Adult,
pubmed-meshheading:17283363-Aged,
pubmed-meshheading:17283363-Aged, 80 and over,
pubmed-meshheading:17283363-Antigens, CD38,
pubmed-meshheading:17283363-Apoptosis,
pubmed-meshheading:17283363-Chromosome Aberrations,
pubmed-meshheading:17283363-Female,
pubmed-meshheading:17283363-Genes, p53,
pubmed-meshheading:17283363-Humans,
pubmed-meshheading:17283363-Immunoglobulin Heavy Chains,
pubmed-meshheading:17283363-Immunoglobulin Variable Region,
pubmed-meshheading:17283363-Leukemia, Lymphocytic, Chronic, B-Cell,
pubmed-meshheading:17283363-Male,
pubmed-meshheading:17283363-Middle Aged,
pubmed-meshheading:17283363-Mutation,
pubmed-meshheading:17283363-Prospective Studies,
pubmed-meshheading:17283363-ZAP-70 Protein-Tyrosine Kinase
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997.
|
|
pubmed:affiliation |
Eastern Cooperative Oncology Group, Division of Hematology-Oncology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA. michael.grever@osumc.edu
|
|
pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Clinical Trial, Phase III,
Research Support, N.I.H., Extramural
|
