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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2007-5-24
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pubmed:abstractText |
Regulatory T-cells (Treg) are natural suppressors of autoimmunity. Previous studies indicate that immunosuppressive drugs, especially calcineurin-inhibitors, may interfere with Treg homeostasis. Inflammatory bowel disease (IBD) can relapse or develop de novo after liver transplantation. IBD is associated with a relative deficiency of Treg. The aim of this study was to determine the effect of long-term immunosuppression on the presence of Treg in the noninflamed colonic mucosa of liver transplant recipients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD3,
http://linkedlifedata.com/resource/pubmed/chemical/FOXP3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Forkhead Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Immunosuppressive Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-10,
http://linkedlifedata.com/resource/pubmed/chemical/RNA,
http://linkedlifedata.com/resource/pubmed/chemical/Smad3 Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Smad7 Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1078-0998
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
703-9
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pubmed:meshHeading |
pubmed-meshheading:17230494-Adult,
pubmed-meshheading:17230494-Aged,
pubmed-meshheading:17230494-Antigens, CD3,
pubmed-meshheading:17230494-Autoimmunity,
pubmed-meshheading:17230494-Biopsy,
pubmed-meshheading:17230494-Colon,
pubmed-meshheading:17230494-Disease Progression,
pubmed-meshheading:17230494-Forkhead Transcription Factors,
pubmed-meshheading:17230494-Gene Expression,
pubmed-meshheading:17230494-Graft Rejection,
pubmed-meshheading:17230494-Humans,
pubmed-meshheading:17230494-Immunohistochemistry,
pubmed-meshheading:17230494-Immunosuppression,
pubmed-meshheading:17230494-Immunosuppressive Agents,
pubmed-meshheading:17230494-Interleukin-10,
pubmed-meshheading:17230494-Intestinal Mucosa,
pubmed-meshheading:17230494-Liver Diseases,
pubmed-meshheading:17230494-Liver Transplantation,
pubmed-meshheading:17230494-Male,
pubmed-meshheading:17230494-Middle Aged,
pubmed-meshheading:17230494-RNA,
pubmed-meshheading:17230494-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17230494-Smad3 Protein,
pubmed-meshheading:17230494-Smad7 Protein,
pubmed-meshheading:17230494-T-Lymphocytes, Regulatory,
pubmed-meshheading:17230494-Transforming Growth Factor beta
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pubmed:year |
2007
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pubmed:articleTitle |
Effects of different immunosuppressive regimens on regulatory T-cells in noninflamed colon of liver transplant recipients.
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pubmed:affiliation |
Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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