rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
2007-1-5
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pubmed:abstractText |
Cold acclimation induces an adaptative increase in respiration in brown adipose tissue (BAT). A comparative analysis by two-dimensional differential in-gel electrophoresis of mitochondrial protein patterns found in rat control and cold-acclimated BAT was performed. A total of 58 proteins exhibiting significant differences in their abundance was unambiguously identified. Proteins implicated in the major catabolic pathways were up-regulated as were ATP synthase and mitofilin. Moreover, these results support the fact that adipocytes can balance their ATP synthesis and their heat production linked to UCP1-sustained uncoupling.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
1535-3893
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
6
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
25-33
|
pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17203945-ATP Synthetase Complexes,
pubmed-meshheading:17203945-Acclimatization,
pubmed-meshheading:17203945-Adipocytes,
pubmed-meshheading:17203945-Adipose Tissue, Brown,
pubmed-meshheading:17203945-Animals,
pubmed-meshheading:17203945-Body Temperature Regulation,
pubmed-meshheading:17203945-Cold Temperature,
pubmed-meshheading:17203945-Electrophoresis, Gel, Two-Dimensional,
pubmed-meshheading:17203945-Ion Channels,
pubmed-meshheading:17203945-Male,
pubmed-meshheading:17203945-Mitochondria,
pubmed-meshheading:17203945-Mitochondrial Proteins,
pubmed-meshheading:17203945-Proteomics,
pubmed-meshheading:17203945-Rats,
pubmed-meshheading:17203945-Rats, Wistar
|
pubmed:year |
2007
|
pubmed:articleTitle |
Mitoproteome plasticity of rat brown adipocytes in response to cold acclimation.
|
pubmed:affiliation |
Laboratory of Bioenergetics, and Centre de Recherche en Neurobiologie Cellulaire et Moléculaire, Liège, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|