Linked Life Data

17201686

Source:http://linkedlifedata.com/resource/pubmed/id/17201686

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2007-5-2
pubmed:abstractText
Arabinogalactan proteins is an umbrella term applied to a highly diverse class of cell surface glycoproteins, many of which contain glycosylphosphatidylinositol lipid anchors. The structures of protein and glycan moieties of arabinogalactan proteins are overwhelmingly diverse while the "hydroxproline contiguity hypothesis" predicts arabinogalactan modification of members of many families of extracellular proteins. Descriptive studies using monoclonal antibodies reacting with carbohydrate epitopes on arabinogalactan proteins and experimental work using beta-Yariv reagent implicate arabinogalactan proteins in many biological processes of cell proliferation and survival, pattern formation and growth, and in plant microbe interaction. Advanced structural understanding of arabinogalactan proteins and an emerging molecular genetic definition of biological roles of individual arabinogalactan protein species, in conjunction with potentially analogous extracellular matrix components of animals, stimulate hypotheses about their mode of action. Arabinogalactan proteins might be soluble signals, or might act as modulators and coreceptors of apoplastic morphogens; their amphiphilic molecular nature makes them prime candidates of mediators between the cell wall, the plasma membrane, and the cytoplasm.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1543-5008
pubmed:author
pubmed:issnType
Print
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
137-61
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
The biology of arabinogalactan proteins.
pubmed:affiliation
Department of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Colney, Norwich, United Kingdom. georg.seifert@boku.ac.at
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't