| pubmed-article:1716541 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1716541 | lifeskim:mentions | umls-concept:C1516213 | lld:lifeskim |
| pubmed-article:1716541 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
| pubmed-article:1716541 | lifeskim:mentions | umls-concept:C0004358 | lld:lifeskim |
| pubmed-article:1716541 | lifeskim:mentions | umls-concept:C1413227 | lld:lifeskim |
| pubmed-article:1716541 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:1716541 | pubmed:dateCreated | 1991-10-24 | lld:pubmed |
| pubmed-article:1716541 | pubmed:abstractText | We have determined the percentage of CD5+ B lymphocytes in the peripheral blood of cancer patients and healthy controls, using antibodies directed at the CD5 and CD19 (pan-B) markers. The frequencies of CD5+ B cells, expressed as a percentage of total B cells, ranged from 14.3 to 57.5% in the controls and from 14.8 to 82.8% in the patient population. One-third of the cancer patients had frequencies greater than 2 s.d. above the mean of the control population. The CD5+ B cell fraction expressed as a percentage of total lymphocytes was also significantly elevated in this group of cancer patients. These results suggest that the CD5+ B cell compartment may be affected by the malignant process or by the therapy modality employed. The plasma levels of several naturally occurring autoantibodies, the products of the CD5+ B cells, were also assessed in cancer patients and controls. No significant differences were observed when reactivity to several autoantigens was measured. These included nuclear components and phospholipids. | lld:pubmed |
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| pubmed-article:1716541 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1716541 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1716541 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1716541 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1716541 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:1716541 | pubmed:issn | 0009-9104 | lld:pubmed |
| pubmed-article:1716541 | pubmed:author | pubmed-author:WitzI PIP | lld:pubmed |
| pubmed-article:1716541 | pubmed:author | pubmed-author:GoldenbergD... | lld:pubmed |
| pubmed-article:1716541 | pubmed:author | pubmed-author:SteinRR | lld:pubmed |
| pubmed-article:1716541 | pubmed:author | pubmed-author:YronII | lld:pubmed |
| pubmed-article:1716541 | pubmed:author | pubmed-author:OvadiaJJ | lld:pubmed |
| pubmed-article:1716541 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1716541 | pubmed:volume | 85 | lld:pubmed |
| pubmed-article:1716541 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1716541 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1716541 | pubmed:pagination | 418-23 | lld:pubmed |
| pubmed-article:1716541 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:1716541 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1716541 | pubmed:articleTitle | CD5+ B cells and naturally occurring autoantibodies in cancer patients. | lld:pubmed |
| pubmed-article:1716541 | pubmed:affiliation | Garden State Cancer Center, Newark, NJ 07103. | lld:pubmed |
| pubmed-article:1716541 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1716541 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:1716541 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
