Increased levels of dopamine transporter (DAT) binding have been reported in patients with major depression. We used the selective DAT radiopharmaceutical Tc-TRODAT-1 and SPECT brain imaging, to examine differences in DAT levels in healthy subjects with and without depressive affect.
Department of Radiology, Division of Nuclear Medicine, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA. andrew.newberg@uphs.upenn.edu
