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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1976-1-29
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pubmed:abstractText |
Antibody activity to herpesvirus hominis type 2 (HVH-2) in 151 women cured of cervical carcinoma (60 in situ, 91 invasive) and in 106 controls differed significantly, especially between the in situ (73%) and control (17%) groups. Sera of 57 patients with cervical atypia showed an increased antibody activity to HVH-2 (58%), compared with that of the 57 matched controls (23%). Antibodies to cytomegalovirus (CMV) were detected more frequently in sera of women with atypia (61%) than in sera of women with cervical disorders other than atypia (42%) or in sera of healthy controls (33%). HVH antigens were present in cervical cells from patients with atypia and from matched controls. Not only exfoliated (imprints) but also cultured and cocultured cervical cells contained HVH antigens; there was no correlation between antigen positivity and antibody activity to HVH-2. Our data further supported the association between HVH-2 and cervical anaplasia and indicated that CMV may also be implicated in its etiology.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
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pubmed:issn |
0027-8874
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
55
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
775-81
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:171424-Adult,
pubmed-meshheading:171424-Aged,
pubmed-meshheading:171424-Antibodies, Viral,
pubmed-meshheading:171424-Antigens, Viral,
pubmed-meshheading:171424-Carcinoma in Situ,
pubmed-meshheading:171424-Cells, Cultured,
pubmed-meshheading:171424-Cytomegalovirus,
pubmed-meshheading:171424-Female,
pubmed-meshheading:171424-Humans,
pubmed-meshheading:171424-Middle Aged,
pubmed-meshheading:171424-Simplexvirus,
pubmed-meshheading:171424-Uterine Cervical Diseases,
pubmed-meshheading:171424-Uterine Cervical Neoplasms
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pubmed:year |
1975
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pubmed:articleTitle |
Herpesvirus antibodies and antigens in patients with cervical anaplasia and in controls.
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pubmed:publicationType |
Journal Article,
Comparative Study
|