| pubmed-article:1713111 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1713111 | lifeskim:mentions | umls-concept:C0023916 | lld:lifeskim |
| pubmed-article:1713111 | lifeskim:mentions | umls-concept:C1013854 | lld:lifeskim |
| pubmed-article:1713111 | lifeskim:mentions | umls-concept:C0018497 | lld:lifeskim |
| pubmed-article:1713111 | lifeskim:mentions | umls-concept:C0027793 | lld:lifeskim |
| pubmed-article:1713111 | lifeskim:mentions | umls-concept:C0178719 | lld:lifeskim |
| pubmed-article:1713111 | lifeskim:mentions | umls-concept:C0682680 | lld:lifeskim |
| pubmed-article:1713111 | lifeskim:mentions | umls-concept:C0019941 | lld:lifeskim |
| pubmed-article:1713111 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:1713111 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:1713111 | pubmed:dateCreated | 1991-8-29 | lld:pubmed |
| pubmed-article:1713111 | pubmed:abstractText | Intracellular records with glass microelectrodes filled with horseradish peroxidase (HRP) were taken from primary afferents of the horizontal semicircular canal in the lizard, Calotes versicolor. A coefficient of variation (CV) of the interspike intervals of spontaneous action potentials (APs) was calculated and correlated with the terminal morphologies of afferents within the canal crista. Irregular fibers with CV greater than 0.4 always correlated with a nerve chalice or calyx afferent terminal expansion surrounding one or more type I hair cells; more regular fibers with CV less than 0.4 always correlated with a dimorphic or bouton only terminal expansion of afferents. Afferents with a CV greater than 0.4 demonstrated miniature excitatory postsynaptic potentials (mEPSPs) that summated to initiate APs. APs were blocked by tetrodotoxin and mEPSP frequency was modulated by caloric stimulation. Cobalt application reversibly blocked mEPSPs. Electron microscopic examination of physiologically studied afferents with CV greater than 0.4 revealed synaptic profiles consisting of typical synaptic bodies and synaptic vesicles in the type I hair cell presynaptic to the nerve chalice. Examples of the interspike baseline in regular and irregular afferents suggest differential modes of impulse initiation in these two fiber types. | lld:pubmed |
| pubmed-article:1713111 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1713111 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1713111 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1713111 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1713111 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1713111 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1713111 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1713111 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1713111 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:1713111 | pubmed:issn | 0006-8993 | lld:pubmed |
| pubmed-article:1713111 | pubmed:author | pubmed-author:HighsteinS... | lld:pubmed |
| pubmed-article:1713111 | pubmed:author | pubmed-author:SchesselD ADA | lld:pubmed |
| pubmed-article:1713111 | pubmed:author | pubmed-author:GinzbergRR | lld:pubmed |
| pubmed-article:1713111 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1713111 | pubmed:day | 22 | lld:pubmed |
| pubmed-article:1713111 | pubmed:volume | 544 | lld:pubmed |
| pubmed-article:1713111 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1713111 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1713111 | pubmed:pagination | 1-16 | lld:pubmed |
| pubmed-article:1713111 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:1713111 | pubmed:meshHeading | pubmed-meshheading:1713111-... | lld:pubmed |
| pubmed-article:1713111 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1713111 | pubmed:articleTitle | Morphophysiology of synaptic transmission between type I hair cells and vestibular primary afferents. An intracellular study employing horseradish peroxidase in the lizard, Calotes versicolor. | lld:pubmed |
| pubmed-article:1713111 | pubmed:affiliation | Department of Otolaryngology, Albert Einstein College of Medicine, Bronx, NY. | lld:pubmed |
| pubmed-article:1713111 | pubmed:publicationType | Journal Article | lld:pubmed |
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