Source:http://linkedlifedata.com/resource/pubmed/id/17085665
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
21
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pubmed:dateCreated |
2006-11-6
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pubmed:abstractText |
The Calvert formula is a widely applied algorithm for the a priori dosing of carboplatin based on patients glomerular filtration rate (GFR) as accurately measured using the 51Cr-EDTA clearance. Substitution of the GFR in this formula by an estimate of creatinine clearance or GFR as calculated by formulae using serum creatinine (SCR; Cockcroft-Gault, Jelliffe, and Wright) is, however, routine clinical practice in many hospitals. The goal of this study was to validate this practice retrospectively in a large heterogeneous adult patient population.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1078-0432
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6502-8
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pubmed:meshHeading |
pubmed-meshheading:17085665-Adolescent,
pubmed-meshheading:17085665-Adult,
pubmed-meshheading:17085665-Aged,
pubmed-meshheading:17085665-Algorithms,
pubmed-meshheading:17085665-Antineoplastic Agents,
pubmed-meshheading:17085665-Area Under Curve,
pubmed-meshheading:17085665-Carboplatin,
pubmed-meshheading:17085665-Creatinine,
pubmed-meshheading:17085665-Female,
pubmed-meshheading:17085665-Glomerular Filtration Rate,
pubmed-meshheading:17085665-Humans,
pubmed-meshheading:17085665-Kidney,
pubmed-meshheading:17085665-Kidney Function Tests,
pubmed-meshheading:17085665-Male,
pubmed-meshheading:17085665-Middle Aged,
pubmed-meshheading:17085665-Neoplasms
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pubmed:year |
2006
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pubmed:articleTitle |
Flat dosing of carboplatin is justified in adult patients with normal renal function.
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pubmed:affiliation |
Department of Pharmacy and Pharmacology, The Netherlands Cancer Institute/Slotervaart Hospital, Amsterdam, and Faculty of Pharmaceutical Sciences, Utrecht University, the Netherlands. apcek@slz.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Validation Studies
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