rdf:type |
|
lifeskim:mentions |
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pubmed:issue |
11
|
pubmed:dateCreated |
2006-11-1
|
pubmed:abstractText |
Previous studies in Alzheimer's Disease (AD) suggest a benefit from switching from one cholinesterase (ChE) inhibitor to another in the event of treatment failure on the index agent. This observational, open-label study sought to evaluate the efficacy of the ChE inhibitor rivastigmine on cognition, functional autonomy and behavior in patients with mild-to-moderate AD previously treated with other ChE inhibitors (switched patients) as well as in those previously ChE-inhibitor-naive (de novo users).
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
pubmed:issn |
1473-4877
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:volume |
22
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
2251-65
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pubmed:meshHeading |
pubmed-meshheading:17076986-Aged,
pubmed-meshheading:17076986-Aged, 80 and over,
pubmed-meshheading:17076986-Alzheimer Disease,
pubmed-meshheading:17076986-Behavior,
pubmed-meshheading:17076986-Caregivers,
pubmed-meshheading:17076986-Cholinesterase Inhibitors,
pubmed-meshheading:17076986-Cognition,
pubmed-meshheading:17076986-Dose-Response Relationship, Drug,
pubmed-meshheading:17076986-Female,
pubmed-meshheading:17076986-Humans,
pubmed-meshheading:17076986-Male,
pubmed-meshheading:17076986-Personal Autonomy,
pubmed-meshheading:17076986-Phenylcarbamates,
pubmed-meshheading:17076986-Prospective Studies,
pubmed-meshheading:17076986-Psychiatric Status Rating Scales,
pubmed-meshheading:17076986-Severity of Illness Index,
pubmed-meshheading:17076986-Treatment Outcome
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pubmed:year |
2006
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pubmed:articleTitle |
A large, naturalistic, community-based study of rivastigmine in mild-to-moderate AD: the EXTEND Study.
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pubmed:affiliation |
McGill Centre for Studies in Aging, Douglas Hospital, Montreal, Quebec, Canada. serge.gauthier@mcgill.ca
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pubmed:publicationType |
Journal Article,
Clinical Trial
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