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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2006-10-19
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pubmed:abstractText |
Chlorpyrifos (CPF) is a common organophosphate (OP) insecticide that has been widely used in extensive agriculture as a pesticide. The primary mechanism of acute toxic action of OPs is inhibition of acetylcholinesterase (AChE). However, targets other than AChE have been proposed to contribute to the acute lethal action and side effects of short- or long-term exposure to these compounds. Bekkedal et al. (Sci Total Environ 274:119-123;2001) showed that chronic administration of the OP trimethylolpropane phosphate (TMPP) reduces the number of schedule-induced polydipsia (SIP) sessions necessary to induce asymptotic drinking level.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0033-3158
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
189
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
47-57
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pubmed:meshHeading |
pubmed-meshheading:17016712-Acetylcholinesterase,
pubmed-meshheading:17016712-Animals,
pubmed-meshheading:17016712-Behavior, Animal,
pubmed-meshheading:17016712-Brain,
pubmed-meshheading:17016712-Chlorpyrifos,
pubmed-meshheading:17016712-Cholinergic Agonists,
pubmed-meshheading:17016712-Cholinergic Antagonists,
pubmed-meshheading:17016712-Cholinesterase Inhibitors,
pubmed-meshheading:17016712-Drinking Behavior,
pubmed-meshheading:17016712-GABA Antagonists,
pubmed-meshheading:17016712-GABA Modulators,
pubmed-meshheading:17016712-Impulsive Behavior,
pubmed-meshheading:17016712-Insecticides,
pubmed-meshheading:17016712-Male,
pubmed-meshheading:17016712-Neurotoxicity Syndromes,
pubmed-meshheading:17016712-Rats,
pubmed-meshheading:17016712-Rats, Wistar,
pubmed-meshheading:17016712-Reinforcement Schedule,
pubmed-meshheading:17016712-Time Factors
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pubmed:year |
2006
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pubmed:articleTitle |
Vulnerability of long-term neurotoxicity of chlorpyrifos: effect on schedule-induced polydipsia and a delay discounting task.
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pubmed:affiliation |
Departamento de Neurociencia y Ciencias de la Salud, Universidad de Almería, La Cañada, Almería, 04120, Spain. dcardona@ual.es
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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