Source:http://linkedlifedata.com/resource/pubmed/id/16919459
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
23
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pubmed:dateCreated |
2006-10-23
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pubmed:abstractText |
The oxidative system H2O2/fluorinated alcohol (TFE, HFIP) was used for direct acid- and MeReO3-catalyzed synthesis of 1,2,4,5-tetraoxanes from cyclic (C6, C7, and C12) and acyclic ketones. The influence of ring size and alkyl chain length were studied and antimalarial activities of synthetic 3,3,6,6-tetraalkyl-1,2,4,5-tetraoxanes were determined. Variations in their antimalarial activities were significant, although they share similar electrochemical properties of the peroxide bond.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0968-0896
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
7790-5
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pubmed:meshHeading |
pubmed-meshheading:16919459-Antimalarials,
pubmed-meshheading:16919459-Catalysis,
pubmed-meshheading:16919459-Hydrogen Peroxide,
pubmed-meshheading:16919459-Ketones,
pubmed-meshheading:16919459-Oxidation-Reduction,
pubmed-meshheading:16919459-Structure-Activity Relationship,
pubmed-meshheading:16919459-Tetraoxanes
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pubmed:year |
2006
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pubmed:articleTitle |
Synthesis and antimalarial activities of novel 3,3,6,6-tetraalkyl-1,2,4,5-tetraoxanes.
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pubmed:affiliation |
Laboratory of Organic and Bioorganic Chemistry, Jozef Stefan Institute and Faculty of Chemistry and Chemical Technology of University of Ljubljana, Jamova 39, 1000 Ljubljana, Slovenia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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