Linked Life Data

16880973

Source:http://linkedlifedata.com/resource/pubmed/id/16880973

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2006-8-1
pubmed:abstractText
A unique characteristic of carbohydrates is their structural diversity which is greater than that of many other classes of biological compounds. Carbohydrate-containing natural products show many different biological activities and some of them have been developed as drugs for medical use. The biosynthesis of carbohydrate-containing natural products is catalysed by glycosyltransferases. In this review we will present information on the function of glycosyltransferases involved in the biosynthesis of oligosaccharide antibiotics focusing especially on urdamycins and landomycins, two angucycline antibiotics with interesting antitumor activities. We will also discuss the use of glycosyltransferases in combinatorial biosynthesis to generate new "hybrid" antibiotics.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1742-206X
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
117-26
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Glycosyltransferases involved in the biosynthesis of biologically active natural products that contain oligosaccharides.
pubmed:affiliation
Pharmazeutische Biologie und Biotechnologie, Institut für Pharmazeutische Wissenschaften, Albert-Ludwigs-Universität Freiburg im Breisgau, Stefan-Meier-Strasse 19, 79104 Freiburg, Germany.
pubmed:publicationType
Journal Article, Review