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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2006-10-6
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pubmed:abstractText |
Endometrial cancer is a common gynecologic malignancy among women. The molecular mechanisms involved in the progression of endometrial cancer are unclear, which has hampered the development of an effective treatment. Survivin, a newly identified member of the inhibitor of apoptosis (IAP) family, regulates 2 critical processes in neoplastic transformation: cell proliferation and apoptosis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/BIRC5 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Caspases,
http://linkedlifedata.com/resource/pubmed/chemical/Cysteine Proteinase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Inhibitor of Apoptosis Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Microtubule-Associated Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 1,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 3,
http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-bcl-2,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
107
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
746-56
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:16826583-Adenocarcinoma,
pubmed-meshheading:16826583-Adult,
pubmed-meshheading:16826583-Aged,
pubmed-meshheading:16826583-Apoptosis,
pubmed-meshheading:16826583-Blotting, Western,
pubmed-meshheading:16826583-Caspases,
pubmed-meshheading:16826583-Cell Proliferation,
pubmed-meshheading:16826583-Cysteine Proteinase Inhibitors,
pubmed-meshheading:16826583-Endometrial Neoplasms,
pubmed-meshheading:16826583-Female,
pubmed-meshheading:16826583-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:16826583-Gene Silencing,
pubmed-meshheading:16826583-Humans,
pubmed-meshheading:16826583-Inhibitor of Apoptosis Proteins,
pubmed-meshheading:16826583-Microtubule-Associated Proteins,
pubmed-meshheading:16826583-Middle Aged,
pubmed-meshheading:16826583-Mitogen-Activated Protein Kinase 1,
pubmed-meshheading:16826583-Mitogen-Activated Protein Kinase 3,
pubmed-meshheading:16826583-Neoplasm Proteins,
pubmed-meshheading:16826583-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:16826583-RNA, Messenger,
pubmed-meshheading:16826583-RNA, Neoplasm,
pubmed-meshheading:16826583-RNA, Small Interfering,
pubmed-meshheading:16826583-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16826583-Transfection,
pubmed-meshheading:16826583-Tumor Cells, Cultured
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pubmed:year |
2006
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pubmed:articleTitle |
Inhibition of survivin reduces cell proliferation and induces apoptosis in human endometrial cancer.
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pubmed:affiliation |
Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, People's Republic of China.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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