Source:http://linkedlifedata.com/resource/pubmed/id/16791360
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2A
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pubmed:dateCreated |
2006-6-22
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pubmed:abstractText |
We conducted a 320 year retrospective survey of the history and genealogy of a large Brazilian family with SCA7. The ancestral couple was from the State of Ceará, Brazil, and the genealogical tree was composed of 577 individuals, including 217 males (37.6%), 255 females (44.1%) and 105 individuals of unknown sex (18.1%). Based on collected information, the 118 individuals consistently affected were distributed in generations IV (n=2), V (n=28), VI (n=57), VII (n=25) and VIII (n=6) of the genealogical tree. Sixty affected members are alive, 37 of them (61.6%) live in the Northeast region, 12 (20%) in the Southeast, 9 (15%) in the Center-West and 2 (3.3%) in the North. This genealogical survey was based only on 4 of the 10 children of the ancestral couple since the destiny of the remaining 6 is unknown. We propose that other Brazilian families with SCA7 may have the same genetic origin.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0004-282X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
222-7
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:16791360-Brazil,
pubmed-meshheading:16791360-Female,
pubmed-meshheading:16791360-Genotype,
pubmed-meshheading:16791360-Humans,
pubmed-meshheading:16791360-Male,
pubmed-meshheading:16791360-Pedigree,
pubmed-meshheading:16791360-Phenotype,
pubmed-meshheading:16791360-Retrospective Studies,
pubmed-meshheading:16791360-Spinocerebellar Ataxias
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pubmed:year |
2006
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pubmed:articleTitle |
Spinocerebellar ataxia type 7 (SCA7): family princeps history, genealogy and geographical distribution.
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pubmed:affiliation |
Department of Neurology, School of Medicine at Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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