|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0003451,
umls-concept:C0017262,
umls-concept:C0027950,
umls-concept:C0036536,
umls-concept:C0036537,
umls-concept:C0185117,
umls-concept:C0243192,
umls-concept:C1519658,
umls-concept:C1521761,
umls-concept:C1948023,
umls-concept:C2911684
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|
pubmed:issue |
9
|
|
pubmed:dateCreated |
2006-8-21
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|
pubmed:abstractText |
During pregnancy, the placenta may become exposed to micro-organisms, such as viruses, which may pose a substantial threat to the embryo/fetus well-being. Recent insight into the immunological capabilities of the trophoblast suggests that the placenta may function as an active barrier by recognizing and responding to pathogens through Toll-like receptors (TLRs).
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pubmed:grant |
|
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
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pubmed:issn |
0268-1161
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
21
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2432-9
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:16751646-Antiviral Agents,
pubmed-meshheading:16751646-Apolipoproteins B,
pubmed-meshheading:16751646-Female,
pubmed-meshheading:16751646-Humans,
pubmed-meshheading:16751646-Ligands,
pubmed-meshheading:16751646-Lipopolysaccharides,
pubmed-meshheading:16751646-Poly I-C,
pubmed-meshheading:16751646-Pregnancy,
pubmed-meshheading:16751646-Pregnancy Trimester, First,
pubmed-meshheading:16751646-RNA, Double-Stranded,
pubmed-meshheading:16751646-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16751646-Toll-Like Receptor 3,
pubmed-meshheading:16751646-Trophoblasts
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|
pubmed:year |
2006
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|
pubmed:articleTitle |
Expression and secretion of antiviral factors by trophoblast cells following stimulation by the TLR-3 agonist, Poly(I : C).
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|
pubmed:affiliation |
Department of Obstetrics, Gynecology & Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural,
Research Support, N.I.H., Intramural
|
