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pubmed-article:16706928pubmed:abstractTextWe report the first isolation and characterization of the canine NKX2-5 gene. This canine homologue has high homology in genomic structure and functional domains to other NKX2-5 across a number of different species. Given the critical role of NKX2-5 in cardiac morphogenesis as seen in human and mouse studies of congenital heart defects, the availability of the canine NKX2-5 provides a good starting point for identifying mutations that may be responsible for certain forms of canine congenital heart defects.lld:pubmed
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pubmed-article:16706928pubmed:articleTitleIsolation and characterization of the canine NKX2-5 gene.lld:pubmed
pubmed-article:16706928pubmed:affiliationSection of Internal Medicine, School of Veterinary Medicine, College of Veterinary Medicine, Kangwon National University, Chuncheon, Korea. hyun5188@kangwon.ac.krlld:pubmed
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