rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
18
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pubmed:dateCreated |
2006-6-19
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pubmed:abstractText |
Cardiotoxicity precludes the concurrent use of doxorubicin and trastuzumab. Because pegylated liposomal doxorubicin (PLD) has equal efficacy but significantly less cardiotoxicity than conventional doxorubicin, this phase II study assessed the rate of cardiotoxicity and efficacy of first-line PLD plus trastuzumab in HER-2-positive metastatic breast cancer (MBC).
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, Humanized,
http://linkedlifedata.com/resource/pubmed/chemical/Doxorubicin,
http://linkedlifedata.com/resource/pubmed/chemical/Polyethylene Glycols,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, erbB-2,
http://linkedlifedata.com/resource/pubmed/chemical/pegylated liposomal doxorubicin,
http://linkedlifedata.com/resource/pubmed/chemical/trastuzumab
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1527-7755
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:day |
20
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2773-8
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:16682726-Adult,
pubmed-meshheading:16682726-Aged,
pubmed-meshheading:16682726-Antibodies, Monoclonal,
pubmed-meshheading:16682726-Antibodies, Monoclonal, Humanized,
pubmed-meshheading:16682726-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:16682726-Breast Neoplasms,
pubmed-meshheading:16682726-Doxorubicin,
pubmed-meshheading:16682726-Female,
pubmed-meshheading:16682726-Heart,
pubmed-meshheading:16682726-Heart Failure,
pubmed-meshheading:16682726-Humans,
pubmed-meshheading:16682726-Middle Aged,
pubmed-meshheading:16682726-Neoplasm Metastasis,
pubmed-meshheading:16682726-Polyethylene Glycols,
pubmed-meshheading:16682726-Receptor, erbB-2,
pubmed-meshheading:16682726-Survival Analysis,
pubmed-meshheading:16682726-Ventricular Dysfunction, Left
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pubmed:year |
2006
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pubmed:articleTitle |
Pegylated liposomal doxorubicin and trastuzumab in HER-2 overexpressing metastatic breast cancer: a multicenter phase II trial.
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pubmed:affiliation |
British Columbia Cancer Agency, Vancouver Cancer Centre, Vancouver, BC, Canada. schia@bccancer.bc.ca
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase II
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