Source:http://linkedlifedata.com/resource/pubmed/id/16677249
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2006-5-8
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pubmed:abstractText |
Granulocyte exocytosis is proposed to be critically dependent on the interaction of soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptors (SNAREs) located on granules/vesicles (v-SNAREs) and plasma membrane (t-SNAREs). Previous studies indicated that the v-SNARE, vesicle-associated membrane protein (VAMP)-2, as well as t-SNAREs (SNAP-23, syntaxin-4 and -6) are implicated in exocytosis from human granulocytes. Vesicle-associated membrane proteins-7 and -8 have been implicated in endosome/lysosome trafficking, however, their role in granulocyte exocytosis remains obscure.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0105-4538
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
777-84
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pubmed:dateRevised |
2008-9-11
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pubmed:meshHeading |
pubmed-meshheading:16677249-Blotting, Western,
pubmed-meshheading:16677249-Cell Fractionation,
pubmed-meshheading:16677249-Cell Membrane,
pubmed-meshheading:16677249-Cell Membrane Permeability,
pubmed-meshheading:16677249-Cytoplasmic Granules,
pubmed-meshheading:16677249-Cytosol,
pubmed-meshheading:16677249-Eosinophils,
pubmed-meshheading:16677249-Exocytosis,
pubmed-meshheading:16677249-Flow Cytometry,
pubmed-meshheading:16677249-Humans,
pubmed-meshheading:16677249-Immunoprecipitation,
pubmed-meshheading:16677249-Neutrophils,
pubmed-meshheading:16677249-Protein Isoforms,
pubmed-meshheading:16677249-R-SNARE Proteins
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pubmed:year |
2006
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pubmed:articleTitle |
A critical role for vesicle-associated membrane protein-7 in exocytosis from human eosinophils and neutrophils.
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pubmed:affiliation |
Pulmonary Research Group, Department of Medicine, University of Alberta, Edmonton, AB, Canada, and Department of Medicine and Immunology, Mayo Clinic, Rochester, MN, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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