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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2006-4-25
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pubmed:abstractText |
Increased plasma homocysteine levels have been found in patients with primary open angle glaucoma (POAG) and glaucoma secondary to pseudoexfoliation syndrome (PEXG). A common polymorphism of the methylenetetrahydrofolatereductase (MTHFR 677C>T) leads to moderately elevated plasma homocysteine levels particularly under conditions of impaired folate status. It was the aim of this study to investigate a hypothesized association between this polymorphism and the presence of either POAG or PEXG.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1090-0535
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
356-9
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pubmed:meshHeading |
pubmed-meshheading:16636653-Aged,
pubmed-meshheading:16636653-Aged, 80 and over,
pubmed-meshheading:16636653-Case-Control Studies,
pubmed-meshheading:16636653-Cytosine,
pubmed-meshheading:16636653-Exfoliation Syndrome,
pubmed-meshheading:16636653-Female,
pubmed-meshheading:16636653-Gene Frequency,
pubmed-meshheading:16636653-Genetic Predisposition to Disease,
pubmed-meshheading:16636653-Genotype,
pubmed-meshheading:16636653-Glaucoma, Open-Angle,
pubmed-meshheading:16636653-Humans,
pubmed-meshheading:16636653-Male,
pubmed-meshheading:16636653-Methylenetetrahydrofolate Reductase (NADPH2),
pubmed-meshheading:16636653-Odds Ratio,
pubmed-meshheading:16636653-Polymorphism, Genetic,
pubmed-meshheading:16636653-Thymine
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pubmed:year |
2006
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pubmed:articleTitle |
Methylenetetrahydrofolatereductase (MTHFR) 677C>T polymorphism and open angle glaucoma.
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pubmed:affiliation |
University Clinic for Ophthalmology, Medical University of Graz, Graz, Austria. mossboeckg@gmx.net
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pubmed:publicationType |
Journal Article
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