Source:http://linkedlifedata.com/resource/pubmed/id/16552953
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2006-3-23
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pubmed:abstractText |
Previous studies have showed that chromosome 7q occurs a high frequency of loss of heterozygosity (LOH) in primary gastric carcinoma; D7S486 located in 7q31 is a locus with the highest frequency of LOH on 7q, which is significantly related to lymph node metastasis of tumor. Gastric carcinoma-related tumor suppressor genes (TSGs) might locate near the locus. In order to seek gastric carcinoma-related TSGs in a further narrow region, LOH of microsatellite marker loci on chromosome 7q31 was examined in primary gastric carcinoma to determine the minimal commonly deleted regions, and the possible roles of these regional deletions in gastric carcinoma pathogenesis were analyzed in this study.
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pubmed:language |
chi
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1000-467X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1306-11
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pubmed:meshHeading |
pubmed-meshheading:16552953-Adenocarcinoma,
pubmed-meshheading:16552953-Adult,
pubmed-meshheading:16552953-Aged,
pubmed-meshheading:16552953-Carcinoma, Signet Ring Cell,
pubmed-meshheading:16552953-Chromosome Deletion,
pubmed-meshheading:16552953-Chromosomes, Human, Pair 7,
pubmed-meshheading:16552953-DNA, Neoplasm,
pubmed-meshheading:16552953-Female,
pubmed-meshheading:16552953-Genes, Tumor Suppressor,
pubmed-meshheading:16552953-Humans,
pubmed-meshheading:16552953-Loss of Heterozygosity,
pubmed-meshheading:16552953-Lymphatic Metastasis,
pubmed-meshheading:16552953-Male,
pubmed-meshheading:16552953-Microsatellite Repeats,
pubmed-meshheading:16552953-Middle Aged,
pubmed-meshheading:16552953-Neoplasm Staging,
pubmed-meshheading:16552953-Stomach Neoplasms
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pubmed:year |
2005
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pubmed:articleTitle |
[Minimal commonly deleted regions on chromosome 7q31 in primary gastric carcinoma and its clinical significance].
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pubmed:affiliation |
State Key Laboratory of Oncology in Southern China, Guangzhou, Guangdong, 510060, PR China. lijintian006@yahoo.com.cn
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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