rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2006-3-13
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pubmed:abstractText |
Acetaminophen toxicity is the most common cause of acute liver failure (ALF) in the United States and Great Britain, but may be underrecognized in certain settings. Acetaminophen-protein adducts are specific biomarkers of drug-related toxicity in animal models and can be measured in tissue or blood samples. Measurement of serum adducts might improve diagnostic accuracy in acute liver failure (ALF) patients.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0016-5085
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pubmed:author |
pubmed-author:Acute Liver Failure Study Group,
pubmed-author:DavernTimothy JTJ2nd,
pubmed-author:FontanaRobert JRJ,
pubmed-author:HinsonJack AJA,
pubmed-author:JamesLaura PLP,
pubmed-author:LalaniEzminaE,
pubmed-author:LarsonAnne MAM,
pubmed-author:LeeWilliam MWM,
pubmed-author:MunozSantiagoS,
pubmed-author:PolsonJulieJ,
pubmed-author:ShakilA ObaidAO
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pubmed:issnType |
Print
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pubmed:volume |
130
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
687-94
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16530510-Acetaminophen,
pubmed-meshheading:16530510-Acetylcysteine,
pubmed-meshheading:16530510-Adolescent,
pubmed-meshheading:16530510-Blood Proteins,
pubmed-meshheading:16530510-Chromatography, High Pressure Liquid,
pubmed-meshheading:16530510-Female,
pubmed-meshheading:16530510-Humans,
pubmed-meshheading:16530510-Liver Failure, Acute,
pubmed-meshheading:16530510-Male,
pubmed-meshheading:16530510-Middle Aged,
pubmed-meshheading:16530510-Poisoning
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pubmed:year |
2006
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pubmed:articleTitle |
Measurement of serum acetaminophen-protein adducts in patients with acute liver failure.
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pubmed:affiliation |
University of California at San Francisco, San Francisco, California, USA. timothy.davern@ucsf.edu [corrected]
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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